MMP-8 Inhibitor I (Synonyms: Matrix Metalloproteinase-8 Inhibitor I) |
| Catalog No.GC18616 |
MMP-8 Inhibitor I is a selective inhibitor of the neutrophil collagenase matrix metalloproteinase-8 (MMP-8) with an IC50 value of 4 nM.
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Cas No.: 236403-25-1
Sample solution is provided at 25 µL, 10mM.
MMP-8 Inhibitor I is a selective inhibitor of the neutrophil collagenase matrix metalloproteinase-8 (MMP-8) with an IC50 value of 4 nM. This inhibitor does not target the activities of other MMPs in vitro. MMP-8 cleaves interstitial collagens and has exhibited activity in atherosclerotic plaques, angiogenesis, and stem cell mobilization. Additionally, MMP-8 expression is observed in normal mammary epithelial cells, whereas a loss of expression is observed in human ductal carcinoma in situ and the deletion of MMP-8 accelerates tumor onset in a mouse model of aggressive breast cancer.
Review for MMP-8 Inhibitor I
Average Rating: 5 (Based on Reviews and 35 reference(s) in Google Scholar.)
Review for MMP-8 Inhibitor I
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