RAAS
RAAS (renin-angiotensin-aldosterone system) is a hormonal signaling cascade that regulates blood pressure, systemic vascular resistance, sodium balance, fluid volume and tissue perfusion etc. It is associated with hypertension, kidney failure and congestive heart failure etc.
Products Related to RAAS(7)
- GC10257Losartan Potassium (DuP 753)CAS: 124750-99-8Purity: >99.50%
Losartan Potassium (DuP 753) (DuP-753 potassium) is an angiotensin II receptor type 1 (AT1) antagonist, competing with the binding of angiotensin II to AT1 with an IC50 of 20 nM.
- GC13078Imidapril HClCAS: 89396-94-1Purity: >99.50%
Imidapril HCl (TA-6366) is an orally active angiotensin-converting enzyme (ACE) and MMP-9 inhibitor.
- GC15023TelmisattanCAS: 144701-48-4Purity: >99.50%
Telmisattan is a novel, orally active angiotensin II receptor type 1 (AT1) antagonist (IC 50 =9.2nM).
- GC15736Rosuvastatin CalciumCAS: 147098-20-2Purity: >99.50%
Rosuvastatin Calcium is a competitive HMG-CoA reductase inhibitor with an IC 50 value of 11nM.
- GC16978CandesartanCAS: 139481-59-7Purity: >99.00%
Candesartan is an oral blocker of AngII type-1 receptors (AT1R), with an IC 50 value of 0.26nM.
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GC10257 | Losartan Potassium (DuP 753) | 124750-99-8 | >99.50% | |
Losartan Potassium (DuP 753) (DuP-753 potassium) is an angiotensin II receptor type 1 (AT1) antagonist, competing with the binding of angiotensin II to AT1 with an IC50 of 20 nM. | ||||
| GC13078 | Imidapril HCl | 89396-94-1 | >99.50% | |
Imidapril HCl (TA-6366) is an orally active angiotensin-converting enzyme (ACE) and MMP-9 inhibitor. | ||||
| GC15023 | Telmisattan | 144701-48-4 | >99.50% | |
Telmisattan is a novel, orally active angiotensin II receptor type 1 (AT1) antagonist (IC 50 =9.2nM). | ||||
| GC15166 | Perindopril Erbumine | 107133-36-8 | >99.50% | |
ACE inhibitor | ||||
| GC15736 | Rosuvastatin Calcium | 147098-20-2 | >99.50% | |
Rosuvastatin Calcium is a competitive HMG-CoA reductase inhibitor with an IC 50 value of 11nM. | ||||
| GC16978 | Candesartan | 139481-59-7 | >99.00% | |
Candesartan is an oral blocker of AngII type-1 receptors (AT1R), with an IC 50 value of 0.26nM. | ||||
| GC16223 | Captopril | 62571-86-2 | >99.00% | |
Captopril is an orally active angiotensin-converting enzyme (ACE) inhibitor with an IC 50 value of 0.025μM. | ||||
