GLPBio

RAAS

RAAS (renin-angiotensin-aldosterone system) is a hormonal signaling cascade that regulates blood pressure, systemic vascular resistance, sodium balance, fluid volume and tissue perfusion etc. It is associated with hypertension, kidney failure and congestive heart failure etc.

Products Related to RAAS(7)

  • GC10257 structure
    GC10257Losartan Potassium (DuP 753)
    CAS: 124750-99-8
    Purity: >99.50%

    Losartan Potassium (DuP 753) (DuP-753 potassium) is an angiotensin II receptor type 1 (AT1) antagonist, competing with the binding of angiotensin II to AT1 with an IC50 of 20 nM.

  • GC13078 structure
    GC13078Imidapril HCl
    CAS: 89396-94-1
    Purity: >99.50%

    Imidapril HCl (TA-6366) is an orally active angiotensin-converting enzyme (ACE) and MMP-9 inhibitor.

  • GC15023 structure
    GC15023Telmisattan
    CAS: 144701-48-4
    Purity: >99.50%

    Telmisattan is a novel, orally active angiotensin II receptor type 1 (AT1) antagonist (IC 50 =9.2nM).

  • GC15166 structure
    GC15166Perindopril Erbumine
    CAS: 107133-36-8
    Purity: >99.50%

    ACE inhibitor

  • GC15736 structure
    GC15736Rosuvastatin Calcium
    CAS: 147098-20-2
    Purity: >99.50%

    Rosuvastatin Calcium is a competitive HMG-CoA reductase inhibitor with an IC 50 value of 11nM.

  • GC16978 structure
    GC16978Candesartan
    CAS: 139481-59-7
    Purity: >99.00%

    Candesartan is an oral blocker of AngII type-1 receptors (AT1R), with an IC 50 value of 0.26nM.

  • GC16223 structure
    GC16223Captopril
    CAS: 62571-86-2
    Purity: >99.00%

    Captopril is an orally active angiotensin-converting enzyme (ACE) inhibitor with an IC 50 value of 0.025μM.