BMS-8 is a small molecule inhibitor of the interaction between programmed death protein 1 (PD-1) and its ligand programmed cell death ligand 1 (PD-L1) with an IC50 value of 146 nM in a homogeneous time-resolved fluorescence (HTRF) binding assay.
BMS-8
Catalog No.: GC42957Purity:>98.00%
BMS-8 is a small molecule inhibitor of the interaction between programmed death protein 1 (PD-1) and its ligand programmed cell death ligand 1 (PD-L1) with an IC50 value of 146 nM in a homogeneous time-resolved fluorescence (HTRF) binding assay.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1675201-90-7
10mM (in 1mL DMSO)In Stock
$84.00
1
1mgIn Stock
$31.00
1
5mgIn Stock
$77.00
1
10mgIn Stock
$126.00
1
25mgIn Stock
$210.00
1
50mgIn Stock
$322.00
1
| Pack Size | Price | Availability | Quantity | Action |
|---|---|---|---|---|
| 10mM (in 1mL DMSO) | $84.00 | In Stock | 1 | |
| 1mg | $31.00 | In Stock | 1 | |
| 5mg | $77.00 | In Stock | 1 | |
| 10mg | $126.00 | In Stock | 1 | |
| 25mg | $210.00 | In Stock | 1 | |
| 50mg | $322.00 | In Stock | 1 |
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Citations
No citations are currently available for this product. Below are selected publications citing GlpBio products.
Nature641, 529–536 (2025)
Nature628, 630–638 (2024)
Nature632, 686–694 (2024)
Nature618, 1017–1023 (2023)
Nature610, 366–372 (2022)
Cell187(9):2288-2304 (2024)
Cell183(7):1867-1883 (2020)
Science388(6745) (2025)
Science387(6739) (2025)
Science387(6734) (2025)
Cell Research35, 97–116 (2025)
Cell Research34, 683–706 (2024)
Cell Research33, 273–287 (2023)
Cell Research33, 546–561 (2023)
Cell Research33, 904–922 (2023)
Cell Research31, 1291–1307 (2021)
Description
Product Documents
Purity:>98.00%Appearance:A solid
Chemical Properties
CAS No.
1675201-90-7
SMILES
CC1=C(COC2=CC=C(CN3CCCCC3C(O)=O)C=C2Br)C=CC=C1C4=CC=CC=C4
Molecular Formula
C27H28BrNO3
Molecular Weight
494.4
Solubility
Methanol: slightly soluble
Storage
Store at -20°C
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.
CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility
g/mol
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