GLPBio

Histamine Receptor

Histamine receptor has 4 subtypes (H1,H2,H3 and H4) which mediates various biological fuctions, including allergic reaction, gastric acid secretion and inflammation etc.

Products Related to Histamine Receptor(243)

  • GC17564 structure
    GC17564VUF 8430 dihydrobromide
    CAS: 100130-32-3
    Purity: >95.00%

    histamine H4 receptor full agonist

  • GC17585 structure
    GC17585VUF 10460
    CAS: 1028327-66-3
    Purity: >98.00%

    histamine H4 receptor agonist

  • GC17701 structure
    GC17701Clemizole hydrochloride
    CAS: 1163-36-6
    Purity: >99.50%

    An antihistamine and TRPC5 channel blocker

  • GC17743 structure
    GC17743A 987306
    CAS: 1082954-71-9
    Purity: >98%

    H4 receptor antagonist,potent and selective

  • GC17869 structure
    GC17869Histamine Phosphate
    CAS: 51-74-1
    Purity: >98.00%

    Histamine receptor agonist

  • GC17974 structure
    GC17974Latrepirdine dihydrochloride
    CAS: 97657-92-6
    Purity: >98.00%

    Latrepirdine is a neuroactive compound with antagonist activity at histaminergic, α-adrenergic, and serotonergic receptors.

  • GC18198 structure
    GC18198Carebastine
    CAS: 90729-42-3
    Purity: >99.00%

    Carebastine is an active metabolite of ebastine .

  • GC18282 structure
    GC18282Lodoxamide
    CAS: 53882-12-5
    Purity: >99.50%

    Lodoxamide is a potent agonist of GPR35 with an EC50 value of 1.61 nM in a β-arrestin-2 interaction assay using CHO-K1 cells expressing the human receptor.

  • GC18463 structure
    GC18463N-acetyl Histamine
    CAS: 673-49-4
    Purity: >99.50%

    N-acetyl Histamine is a histamine metabolite that is formed via acetyl-CoA-dependent N-acetylation of histamine by AANATL7 in D.

  • GC19178 structure
    GC19178GSK189254A
    CAS: 720690-73-3
    Purity: >98.00%

    GSK189254A (GSK189254) is a novel, potent and selective histamine H3 receptor antagonist with pKi values of 9.59-9.90 and 8.51-9.17 for human and rat H3, respectively.

  • GC19441 structure
    GC19441Levocabastine (hydrochloride)
    CAS: 79547-78-7
    Purity: >98.00%

    Levocabastine is a potent and selective histamine H1 receptor antagonist with an IC50 value of 8.32 nM (Kis = 62.5, 23,500, and 1,937 nM for H1, H2, and H3, respectively) for inhibition of phosphoinositide turnover on human conjunctival epithelial cells.

  • GC25060 structure
    GC25060Amitriptyline
    CAS: 50-48-6
    Purity: >98%

    Amitriptyline (MK-230, N-750, Ro41575) is a tricyclic antidepressant (TCA) with analgesic properties, widely used to treat depression and neuropathic pain. Amitriptyline is an inhibitor of both serotonin transporter (SERT) and norepinephrine transporter (NET) with Ki of 3.45 nM and 13.3 nM, respectively. Amitriptyline also inhibits histamine receptor H1, histamine receptor H4, 5-HT2 and sigma 1 receptor with Ki of 0.5 nM, 7.31 nM, 235 nM and 287 nM, respectively. This product is a waxy solid.

  • GC25136 structure
    GC25136Betazole Dihydrochloride
    CAS: 138-92-1
    Purity: >99.00%

    Betazole Dihydrochloride (Ametazole, 2-(3-Pyrazolyl)ethanamine) is a histamine H2 agonist used clinically to test gastric secretory function.

  • GC25571 structure
    GC25571Levocetirizine
    CAS: 130018-77-8
    Purity: >98%

    Levocetirizine (LCZ, (R)-Cetirizine), the R-enantiomer of cetirizine, is an antagonist of histamine H(1) receptor.

  • GC25785 structure
    GC25785Promethazine
    CAS: 60-87-7
    Purity: >98.00%

    Promethazine is a potent histamine H1 receptor antagonist. Promethazine is a medication used in the management and treatment of allergic conditions, nausea and vomiting, motion sickness, and sedation. Promethazine exhibits antiparasitic properties.

  • GC30423 structure
    GC30423CP-66948
    CAS: 101189-47-3
    Purity: >98%

    CP-66948 is a histamine H2-receptor antagonist with gastric antisecretory activity and mucosal protective properties.

  • GC30455 structure
    GC30455Rocastine (AHR-11325)
    CAS: 91833-49-7
    Purity: >98%

    Rocastine (AHR-11325) is a selective, nonsedating H1 antagonist, acting as an antihistamine.

  • GC30496 structure
    GC30496Doxylamine D5 succinate
    CAS: 1216840-94-6
    Purity: >98%

    Doxylamine D5 succinate is deuterium labeled Doxylamine, which is a first generation antihistamine.

  • GC30759 structure
    GC30759H3 receptor-MO-1
    CAS: 1240914-03-7
    Purity: >98%

    H3 receptor-MO-1 is a modulator of histamine H3 receptor.

  • GC30775 structure
    GC30775Histamine (Ergamine)
    CAS: 51-45-6
    Purity: >98.00%

    Histamine (Ergamine) is an organic nitrogenous compound involved in local immune responses as well as regulating physiological function in the gut and acting as a neurotransmitter.

  • GC30821 structure
    GC30821JNJ-39758979
    CAS: 1046447-90-8
    Purity: >98.00%

    JNJ-39758979 is a selective, orally active, and high-affinity histamine H4 receptor antagonist with Kis of 12.5, 5.3, and 25 nM for human, mouse, and monkey histamine H4 receptor, respectively.

  • GC30902 structure
    GC30902Dimenhydrinate
    CAS: 523-87-5
    Purity: >99.50%

    Dimenhydrinate is an anti-emetic and anti-histamine commonly available over-the-counter as a motion sickness remedy.

  • GC30948 structure
    GC30948Chlorphenoxamine
    CAS: 77-38-3
    Purity: >98%

    Chlorphenoxamine is an antihistamine and anticholinergic used as an antipruritic and antiparkinsonian agent.

  • GC30999 structure
    GC30999Pimethixene (Pimetixene)
    CAS: 314-03-4
    Purity: >98%

    Pimethixene (Pimetixene) is antihistamine and antiserotonergic compound, acts as an antimigraine agent.