GLPBio

OX Receptor

OX receptor (orexin receptor) is a G-protein coupled receptor that is involved in the regulation of feeding behaviour.

Products Related to OX Receptor(52)

  • GC37623 structure
    GC37623Seltorexant
    CAS: 1293281-49-8
    Purity: >98.00%

    Seltorexant is an orally active, high-affinity, and selective OX2R antagonist with a pK i value of 8.1 for rat OX2R.

  • GC38352 structure
    GC38352Orexin A (human, rat, mouse) (TFA)
    Purity: >99.00%

    Orexin A human, rat, mouse TFA, a 33 amino acid excitatory neuropeptide, orchestrates diverse central and peripheral processes.

  • GC50142 structure
    GC50142ACT 462206
    CAS: 1361321-96-1
    Purity: >98%

    Potent, dual orexin receptor antagonist

  • GC50559 structure
    GC50559YNT 185
    CAS: 1804978-82-2
    Purity: >98%

    YNT 185 is a nonpeptide, selective orexin type-2 receptor (OX2R) agonist, with EC50s of 0.028 and 2.75 μM for OX2R and OX1R, respectively.

  • GC61770 structure
    GC61770Orexin receptor antagonist 2
    CAS: 1457940-75-8
    Purity: >98.00%

    Orexin receptor antagonist 2 (compound 30) is a potent orexin receptor antagonist with pKis of 7.69 and 9.78.

  • GC63415 structure
    GC63415JNJ-54717793
    CAS: 1628843-99-1
    Purity: >98.50%

    JNJ-54717793, as a brain penetrant, is an orally active, selective and high affinity orexin-1 receptor (OX1R) antagonist (plasma EC50=85 ng/mL).

  • GC64021 structure
    GC64021Orexin B, rat, mouse TFA
    Purity: >98.50%

    Orexin B, rat, mouse (Rat orexin B) TFA is an endogenous orexin receptor agonist.

  • GC64826 structure
    GC64826Vornorexant
    CAS: 1517965-94-4
    Purity: >98%

    Vornorexant (ORN-0829; TS-142) is a potent dual OX1R and OX2R antagonist with IC50 values of 1.05 nM and 1.27 nM, respectively.

  • GC65382 structure
    GC65382Orexin receptor antagonist 5
    CAS: 1352834-55-9
    Purity: >98%
  • GC65550 structure
    GC65550Danavorexton
    CAS: 2114324-48-8
    Purity: >98%

    Danavorexton is an orexin receptor agonist.

  • GC67929 structure
    GC67929Orexin 2 Receptor Agonist 2
    CAS: 2114324-60-4
    Purity: >98.00%

    Orexin 2 Receptor Agonist 2 is a selective orexin 2 receptor agonist.

  • GC67957 structure
    GC67957Orexin A (human, rat, mouse) (acetate)
    Purity: >98%
  • GC68909 structure
    GC68909Cudarolimab
    CAS: 2244739-29-3
    Purity: >95.00%

    Cudarolimab (IBI101) is a fully human anti-OX40 (CD134, a co-stimulatory molecule expressed by activated immune cells) antibody. Cudarolimab inhibits the binding of OX40 to its ligand OX40L. Cudarolimab has anti-tumor activity and can be used in cancer-related research.

  • GC70782 structure
    GC70782Firazorexton
    CAS: 2274802-95-6
    Purity: >99.00%

    Firazorexton (TAK-994 free base) is an orally active, brain-permeable orexin type 2 receptor (OX2R) agonist.

  • GC70783 structure
    GC70783Firazorexton hydrate
    CAS: 2861934-86-1
    Purity: >99.00%

    Firazorexton hydrate (TAK-994) is a potent, brain-penetrant, and orally active orexin type 2 receptor (OX2R) agonist (EC50: 19 nM).

  • GC70784 structure
    GC70784(2R,3R)-Firazorexton
    CAS: 2692692-00-3
    Purity: >99.00%

    (2R,3R)-Firazorexton ((2R,3R)-TAK-994 free base) is an isomer of Firazorexton .

  • GC70995 structure
    GC70995Nivasorexant
    CAS: 1435480-40-2

    Nivasorexant is a potent orexin receptor antagonist.

  • GC71209 structure
    GC71209Fazamorexant
    CAS: 1808918-69-5
    Purity: >99.00%

    Fazamorexant (YZJ-1139) is a potent orexin receptor antagonist.

  • GC71296 structure
    GC71296RTIOXA-43
    CAS: 2832067-72-6
    Purity: >99.00%

    RTIOXA-43 is a orexin receptor agonist with EC50s of 24 nM and 24 nM for OX2 and OX1 receptors, respectively.

  • GC72466 structure
    GC72466Efizonerimod alfa
    CAS: 1635395-27-5
    Purity: >98.00%

    Efizonerimod alfa is a potent monoclonal antibody OX40 activator.

  • GC72472 structure
    GC72472Revdofilimab
    CAS: 2230138-89-1
    Purity: >99.00%

    Revdofilimab (ABBV-368) is a human IgG1 agonist monoclonal antibody against OX40.

  • GC79277 structure
    GC79277Solaprubart
    CAS: 3057433-10-7
    Purity: >99.50%

    Solaprubart (STAR-0310) is a fully human IgG1 subtype monoclonal antibody targeting OX40 (CD134/TNFRSF4), with a K d of 7.2 nM.

  • GC79278 structure
    GC79278Vedastotug
    CAS: 2878367-20-3
    Purity: >99.50%

    Vedastotug is a human monoclonal antibody targeting TNFRSF4/OX40/CD134, with its corresponding isotype control being Human IgG1 kappa, Isotype Control [1] .

  • GC79313 structure
    GC79313Alixorexton enantiomer
    CAS: 2648350-16-5
    Purity: >99.00%

    Alixorexton (ALKS 2680) enantiomer is the enantiomer of Alixorexton.