Apoptosis

Rubropunctatin is an orange nitrogen-containing ketone pigment isolated from the extract of red yeast rice (Monascus purpureus). Rubropunctatin has anti-inflammatory, immunosuppressive and antioxidant properties, as well as anti-tumor activity.

SIRT6 activator 12q is a selective SIRT6 activator (IC₅₀ = 0.58μM).

SLC7A11-IN-1 is an effective inhibitor of SLC7A11. It exhibits anti-proliferative activity and inhibits cell invasion and metastasis. SLC7A11-IN-1 induces apoptosis and cell cycle arrest in the S phase. It has anti-tumor activity.

Thymidine 3',5'-diphosphate (Deoxythymidine 3',5'-diphosphate) tetrasodium is a selective inhibitor of Staphylococcus nuclease and Tudor domain-containing protein 1 (SND1, a component of the microRNA regulatory complex RISC) as well as [3,5-2H2] tyrosyl nuclease. It has anti-tumor activity and can also be used as a catalyst in biochemical reactions.

Yakuchinone A is a natural product that can be isolated from the fruit of Alpinia oxyphylla. It can induce apoptosis (cell death) and has anti-cancer and anti-inflammatory activities.

Thymocartin TFA is the TFA salt form of Thymocartin .

Gallium maltolate (GAM) is an apoptosis inducer with anti-cancer and anti-inflammatory activity.

Peginterferon beta-1a (Peginterferon β-1a) is the first pegylated interferon beta-1a molecule.

Justicidin B is a potent anticancer lignan and proapoptotic agent.

Cipepofol (Ciprofol), a novel 2,6-disubstituted phenol derivative, is a positive allosteric modulator and direct agonist of the GABAA receptor.

RH01386 is a small molecule that can prevent endoplasmic reticulum stress (ERS)-induced β cell dysfunction and death, and inhibits proapoptotic gene expression.

Actinomycin X2 (Actinomycin V), produced by many Streptomyces sp.

9-cis-Retinoic acid-d5 is the deuterium labeled 9-cis-Retinoic acid.

ABT-510 acetate is an anti-angiogenic TSP peptide (Thrombospondin-1 analogue) that induces apoptosis and inhibits ovarian tumour growth in an orthotopic, syngeneic model of epithelial ovarian cancer.

Betamethasone-d5-1 is deuterium labeled Betamethasone.

PDK4-IN-1 is an anthraquinone derivative and a potent and orally active pyruvate dehydrogenase kinase 4 (PDK4) inhibitor with an IC50 value of 84 nM.

Cytarabine-d2 is the deuterium labeled Cytarabine.

AQX-435 is a potent SHIP1 phosphatase activator.

Broussochalcone A is an antioxidant and an inhibitor of Xanthine Oxidase (IC50=2.21 μM), with free radical scavenging activity.

UBX1325 is an Bcl-xL inhibitor that promotes apoptosis in senescent cells.

Diclofenac-d4 (sodium) is the deuterium labeled Diclofenac sodium.

ASK1-IN-4 (Compound 17) is an ASK1 inhibitor (IC50=0.2 μM).

5'-Methylthioadenosine-13C6 is the 13C-labeled 5'-Methylthioadenosine.

Melatonin-d7 is the deuterium labeled Melatonin.