Obesity, Appetite Control & Diabetes
Obesity, Appetite Control & Diabetes
Satiety, appetite, and craving are CNS drives, whereas metabolism and energy utilization are peripheral endocrine actions.
Stephen M. Stahl, M.D., Ph.D. read more
Research Areas
Products Related to Obesity, Appetite Control & Diabetes(354)
- GC44518Osteocalcin (1-49) (human) (trifluoroacetate salt)CAS: 136461-80-8Purity: >95.00%
Osteocalcin (1-49) is a non-collagenous peptide that is secreted by osteoblasts and odontoblasts and comprises 1-2% of the total protein in bone.
- GC44524Oxyntomodulin (bovine, porcine) (trifluoroacetate salt)Purity: >95.00%
Oxyntomodulin, also known as glucagon-37, is a 37-amino acid peptide produced in bovine and porcine gut.
- GC44544Palmitoleic Acid (sodium salt)CAS: 6610-24-8Purity: >95.00%
Palmitoleic acid is an ω-7 monounsaturated fatty acid that is a common constituent of the triglycerides of human adipose tissue.
- GC44598Peptide YY (human) (trifluoroacetate salt)Purity: >95.00%
Peptide YY (human) (trifluoroacetate salt) is a peptide hormone secreted by intestinal L cells.
- GC44645Pioglitazone (potassium salt)CAS: 1266523-09-4Purity: >98.00%
Pioglitazone (U 72107) potassium is an orally active and selective PPARγ (peroxisome proliferator-activated receptor) agonist with high affinity binding to the PPARγ ligand-binding domain with EC50 of 0.93 μM and 0.99 μM for human and mouse PPARγ, respectively.
- GC44660PlatensimycinCAS: 835876-32-9Purity: >95.00%
Platensimycin (PTM) is an antibiotic produced by S.
- GC44775PTP1B InhibitorCAS: 765317-72-4Purity: >98.00%
PTP1B Inhibitor is a non-competitive allosteric inhibitor of the protein tyrosine phosphatase PTP1B, with an IC50 of 8 μM.
- GC44811Remogliflozin etabonateCAS: 442201-24-3Purity: >99.00%
Remogliflozin etabonate is a prodrug form of the sodium-glucose transporter 2 (SGLT2) inhibitor remogliflozin A.
- GC44851Rosiglitazone (potassium salt)CAS: 316371-84-3Purity: >98.00%
Rosiglitazone (BRL 49653) potassium is an orally active selective PPARγ agonist (EC50: 60 nM, Kd: 40 nM).
- GC44895Sitagliptin N-Sulfate (sodium salt)CAS: 2470126-25-9Purity: >95.00%
Sitagliptin N-sulfate is a phase II metabolite of the dipeptidyl peptidase 4 (DPP-4) inhibitor (-)-sitagliptin.
- GC44914Somatostatin-14 (acetate)CAS: 54472-66-1Purity: >98.00%
Somatostatin-14 is a natural cyclic peptide hormone derived from the preprohormone, somatostatin.
- GC45139Vapreotide (trifluoroacetate salt)Purity: >95.00%
Vapreotide is a peptide neurokinin-1 receptor (NK1) antagonist and analog of somatostatin (IC50 = 330 nM in a radioligand binding assay).
- GC45144Vildagliptin carboxylic acid metabolite (trifluoroacetate salt)CAS: 565453-41-0Purity: >98.00%
Vildagliptin carboxylic acid metabolite is the major metabolite of the dipeptidyl peptidase 4 (DPP-4) inhibitor vildagliptin in humans.
- GC45186ZLN005 (hydrochloride)Purity: >98.00%
Peroxisome proliferator-activated receptor-γ coactivator-1α (PGC-1α) is a tissue-specific and inducible transcriptional coactivator for several nuclear receptors and plays a key role in energy metabolism, hepatic gluconeogenesis, and cholesterol homoeostasis.
- GC45252(-)-Sitagliptin Carbamoyl GlucuronideCAS: 940002-59-5Purity: >90.00%
(-)-Sitagliptin carbamoyl glucuronide is a minor phase II metabolite of the dipeptidyl peptidase 4 (DPP-4) inhibitor (-)-sitagliptin.
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GC44518 | Osteocalcin (1-49) (human) (trifluoroacetate salt) | 136461-80-8 | >95.00% | |
Osteocalcin (1-49) is a non-collagenous peptide that is secreted by osteoblasts and odontoblasts and comprises 1-2% of the total protein in bone. | ||||
| GC44524 | Oxyntomodulin (bovine, porcine) (trifluoroacetate salt) | - | >95.00% | |
Oxyntomodulin, also known as glucagon-37, is a 37-amino acid peptide produced in bovine and porcine gut. | ||||
| GC44529 | P053 | 2748196-63-4 | >97.00% | |
P053 is an inhibitor of ceramide synthase 1 (CerS1; IC50s = 0.54 and 0.46 μM for human and mouse CerS1, respectively). | ||||
| GC44544 | Palmitoleic Acid (sodium salt) | 6610-24-8 | >95.00% | |
Palmitoleic acid is an ω-7 monounsaturated fatty acid that is a common constituent of the triglycerides of human adipose tissue. | ||||
| GC44598 | Peptide YY (human) (trifluoroacetate salt) | - | >95.00% | |
Peptide YY (human) (trifluoroacetate salt) is a peptide hormone secreted by intestinal L cells. | ||||
| GC44645 | Pioglitazone (potassium salt) | 1266523-09-4 | >98.00% | |
Pioglitazone (U 72107) potassium is an orally active and selective PPARγ (peroxisome proliferator-activated receptor) agonist with high affinity binding to the PPARγ ligand-binding domain with EC50 of 0.93 μM and 0.99 μM for human and mouse PPARγ, respectively. | ||||
| GC44660 | Platensimycin | 835876-32-9 | >95.00% | |
Platensimycin (PTM) is an antibiotic produced by S. | ||||
| GC44775 | PTP1B Inhibitor | 765317-72-4 | >98.00% | |
PTP1B Inhibitor is a non-competitive allosteric inhibitor of the protein tyrosine phosphatase PTP1B, with an IC50 of 8 μM. | ||||
| GC44811 | Remogliflozin etabonate | 442201-24-3 | >99.00% | |
Remogliflozin etabonate is a prodrug form of the sodium-glucose transporter 2 (SGLT2) inhibitor remogliflozin A. | ||||
| GC44851 | Rosiglitazone (potassium salt) | 316371-84-3 | >98.00% | |
Rosiglitazone (BRL 49653) potassium is an orally active selective PPARγ agonist (EC50: 60 nM, Kd: 40 nM). | ||||
| GC44895 | Sitagliptin N-Sulfate (sodium salt) | 2470126-25-9 | >95.00% | |
Sitagliptin N-sulfate is a phase II metabolite of the dipeptidyl peptidase 4 (DPP-4) inhibitor (-)-sitagliptin. | ||||
| GC44914 | Somatostatin-14 (acetate) | 54472-66-1 | >98.00% | |
Somatostatin-14 is a natural cyclic peptide hormone derived from the preprohormone, somatostatin. | ||||
| GC44954 | Stevioside (hydrate) | - | >95.00% | |
Stevioside is a natural non-caloric sweetener. | ||||
| GC45139 | Vapreotide (trifluoroacetate salt) | - | >95.00% | |
Vapreotide is a peptide neurokinin-1 receptor (NK1) antagonist and analog of somatostatin (IC50 = 330 nM in a radioligand binding assay). | ||||
| GC45144 | Vildagliptin carboxylic acid metabolite (trifluoroacetate salt) | 565453-41-0 | >98.00% | |
Vildagliptin carboxylic acid metabolite is the major metabolite of the dipeptidyl peptidase 4 (DPP-4) inhibitor vildagliptin in humans. | ||||
| GC45164 | WWL229 | 1338575-28-2 | >98.00% | |
Mouse carboxylesterase 3 (Ces3, also named Ces1d) mediates triglyceride hydrolysis in white adipose tissue, liberating free fatty acids into circulation. | ||||
| GC45186 | ZLN005 (hydrochloride) | - | >98.00% | |
Peroxisome proliferator-activated receptor-γ coactivator-1α (PGC-1α) is a tissue-specific and inducible transcriptional coactivator for several nuclear receptors and plays a key role in energy metabolism, hepatic gluconeogenesis, and cholesterol homoeostasis. | ||||
| GC45252 | (-)-Sitagliptin Carbamoyl Glucuronide | 940002-59-5 | >90.00% | |
(-)-Sitagliptin carbamoyl glucuronide is a minor phase II metabolite of the dipeptidyl peptidase 4 (DPP-4) inhibitor (-)-sitagliptin. | ||||
| GC45277 | (±)-Camphene | 79-92-5 | >99.50% | |
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| GC45315 | 1-Palmitoyl-d9-2,3-Dipalmitoyl-sn-glycerol | 2738376-70-8 | >99.00% | |
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| GC45320 | 1-Stearoyl-3-Oleoyl-rac-glycerol | 18266-27-8 | >98.00% | |
| ||||
| GC45379 | Alloxan (hydrate) | 2244-11-3 | >98.00% | |
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| GC45490 | Kisspeptin-54 (human) (trifluoroacetate salt) | - | >95.00% | |
| ||||
| GC45506 | MD001 | 2254605-76-8 | >90.00% | |
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