Drug Metabolite
Drug metabolite results when a drug is metabolized into a modified form which continues to produce effects. Drug metabolism redox reactions such as heteroatom dealkylations, hydroxylations, heteroatom oxygenations, reductions, and dehydrogenations can yield active metabolites, and in rare cases even conjugation reactions can yield an active metabolite.
Products Related to Drug Metabolite(571)
- GC39443Solriamfetol hydrochlorideCAS: 178429-65-7Purity: >99.00%
Solriamfetol hydrochloride is a dopamine and norepinephrine reuptake inhibitor. Solriamfetol hydrochloride blocks the reuptake of dopamine and norepinephrine by presynaptic neurons. Solriamfetol hydrochloride is used to treat daytime sleepiness associated with narcolepsy or obstructive sleep apnea.
- GC396113'-Hydroxy RepaglinideCAS: 874908-14-2Purity: >98.00%
3'-Hydroxy Repaglinide is a main CYP2C8 metabolite of Repaglinide.
- GC39757Etilevodopa hydrochlorideCAS: 39740-30-2Purity: >98.50%
Etilevodopa (L-Dopa ethyl ester) hydrochloride, an ethyl-ester prodrug of Levodopa, is rapidly hydrolyzed to Levodopa and ethanol by nonspecific esterases in the gastrointestinal tract.
- GC398413,4-Dehydro CilostazolCAS: 73963-62-9Purity: >98.00%
3,4-Dehydro Cilostazol (OPC-13015) is an active metabolite of Cilostazol.
- GC40018Donepezil N-oxideCAS: 120013-84-5Purity: >98.00%
Donepezil N-oxide is an active metabolite of the acetylcholinesterase inhibitor donepezil.
- GC40099Leukotriene D4 MaxSpec® StandardCAS: 73836-78-9Purity: >97.00%
Leukotriene D4 MaxSpec® Standard is a potent bronchoconstrictor.
- GC40143DihydrotetrabenazineCAS: 3466-75-9Purity: >98.00%
Dihydrotetrabenazine is an active metabolite of the vesicular monoamine transporter 2 (VMAT2) inhibitor tetrabenazine that is generated by hepatic carbonyl reductases.
- GC40144Levofloxacin N-oxideCAS: 117678-38-3Purity: >95.00%
Levofloxacin N-oxide is an inactive metabolite of the antibiotic levofloxacin.
- GC40145(S)-LaudanosineCAS: 2688-77-9Purity: >98.00%
(S)-Laudanosine is the (S) enantiomer of laudanosine, a metabolite of the neuromuscular blocking agents atracurium and cisatracurium.
- GC40190Febuxostat Acyl GlucuronideCAS: 1351692-92-6Purity: >98.00%
Febuxostat acyl glucuronide is a metabolite of the xanthine oxidoreductase inhibitor febuxostat.
- GC40191Ibuprofen Carboxylic AcidCAS: 15935-54-3Purity: >98.00%
Ibuprofen carboxylic acid is a major metabolite of ibuprofen.
- GC40286(E,Z)-2-propyl-2-Pentenoic AcidCAS: 60218-41-9Purity: >98.00%
(E,Z)-2-propyl-2-Pentenoic acid is a bioactive metabolite of valproic acid that exhibits the same profile and potency of anticonvulsant activity in animal models as its parent compound without any observed teratogenicity and hepatotoxicity.
- GC40298N-acetyl-5-Aminosalicylic AcidCAS: 51-59-2Purity: >98.00%
N-acetyl-5-Aminosalicylic acid is a metabolite of the anti-inflammatory agent 5-aminosalicylic acid and its prodrug form, sulfasalazine.
- GC40300DihydroresveratrolCAS: 58436-28-5Purity: >98.00%
Dihydroresveratrol is a major metabolite of resveratrol that is produced by animal-associated bacteria, including the gut microbiota.
- GC40301Tamoxifen N-oxideCAS: 75504-34-6Purity: >98.00%
Tamoxifen is a selective estrogen receptor modulator that evokes tissue-dependent effects.
- GC40480α-Phenyl-α-(2-pyridyl)acetonitrileCAS: 5005-36-7Purity: >98.00%
α-Phenyl-α-(2-pyridyl)thioacetamide, also known as antigastrin and SC-15396, is an inhibitor of gastric acid secretion.
- GC405297-hydroxy WarfarinCAS: 17834-03-6Purity: >98.00%
7-hydroxy Warfarin is a metabolite of (-)-warfarin, which is a more potent vitamin K antagonist than (+)-warfarin.
- GC40616Des-4-fluorobenzyl MosaprideCAS: 152013-26-8Purity: >96.00%
Des-4-fluorobenzyl Mosapride is the primary metabolite of mosapride.
- GC406752-deoxy-ArtemisininCAS: 72826-63-2Purity: >98.00%
2-deoxy-Artemisinin is an inactive metabolite of the antimalarial agent artemisinin.
- GC40834cis-EntacaponeCAS: 145195-63-7Purity: >98.00%
cis-Entacapone is a metabolite of the catechol-O-methyltransferase (COMT) inhibitor entacapone.
- GC40852N-Demethylerythromycin ACAS: 992-62-1Purity: >95.00%
N-Demethylerythromycin A is a metabolite of erythromycin.
- GC408794-hydroxy Solifenacin N-oxideCAS: 2747991-39-3Purity: >95.00%
4-hydroxy Solifenacin N-oxide is an N-oxide form of 4-hydroxy solifenacin, the major metabolite of solifenacin .
- GC4096821-hydroxy EplerenoneCAS: 334678-67-0Purity: >98.00%
21-hydroxy Eplerenone is a major metabolite of the mineralocorticoid receptor antagonist eplerenone.
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GC39443 | Solriamfetol hydrochloride | 178429-65-7 | >99.00% | |
Solriamfetol hydrochloride is a dopamine and norepinephrine reuptake inhibitor. Solriamfetol hydrochloride blocks the reuptake of dopamine and norepinephrine by presynaptic neurons. Solriamfetol hydrochloride is used to treat daytime sleepiness associated with narcolepsy or obstructive sleep apnea. | ||||
| GC39611 | 3'-Hydroxy Repaglinide | 874908-14-2 | >98.00% | |
3'-Hydroxy Repaglinide is a main CYP2C8 metabolite of Repaglinide. | ||||
| GC39757 | Etilevodopa hydrochloride | 39740-30-2 | >98.50% | |
Etilevodopa (L-Dopa ethyl ester) hydrochloride, an ethyl-ester prodrug of Levodopa, is rapidly hydrolyzed to Levodopa and ethanol by nonspecific esterases in the gastrointestinal tract. | ||||
| GC39841 | 3,4-Dehydro Cilostazol | 73963-62-9 | >98.00% | |
3,4-Dehydro Cilostazol (OPC-13015) is an active metabolite of Cilostazol. | ||||
| GC40018 | Donepezil N-oxide | 120013-84-5 | >98.00% | |
Donepezil N-oxide is an active metabolite of the acetylcholinesterase inhibitor donepezil. | ||||
| GC40099 | Leukotriene D4 MaxSpec® Standard | 73836-78-9 | >97.00% | |
Leukotriene D4 MaxSpec® Standard is a potent bronchoconstrictor. | ||||
| GC40143 | Dihydrotetrabenazine | 3466-75-9 | >98.00% | |
Dihydrotetrabenazine is an active metabolite of the vesicular monoamine transporter 2 (VMAT2) inhibitor tetrabenazine that is generated by hepatic carbonyl reductases. | ||||
| GC40144 | Levofloxacin N-oxide | 117678-38-3 | >95.00% | |
Levofloxacin N-oxide is an inactive metabolite of the antibiotic levofloxacin. | ||||
| GC40145 | (S)-Laudanosine | 2688-77-9 | >98.00% | |
(S)-Laudanosine is the (S) enantiomer of laudanosine, a metabolite of the neuromuscular blocking agents atracurium and cisatracurium. | ||||
| GC40190 | Febuxostat Acyl Glucuronide | 1351692-92-6 | >98.00% | |
Febuxostat acyl glucuronide is a metabolite of the xanthine oxidoreductase inhibitor febuxostat. | ||||
| GC40191 | Ibuprofen Carboxylic Acid | 15935-54-3 | >98.00% | |
Ibuprofen carboxylic acid is a major metabolite of ibuprofen. | ||||
| GC40286 | (E,Z)-2-propyl-2-Pentenoic Acid | 60218-41-9 | >98.00% | |
(E,Z)-2-propyl-2-Pentenoic acid is a bioactive metabolite of valproic acid that exhibits the same profile and potency of anticonvulsant activity in animal models as its parent compound without any observed teratogenicity and hepatotoxicity. | ||||
| GC40298 | N-acetyl-5-Aminosalicylic Acid | 51-59-2 | >98.00% | |
N-acetyl-5-Aminosalicylic acid is a metabolite of the anti-inflammatory agent 5-aminosalicylic acid and its prodrug form, sulfasalazine. | ||||
| GC40300 | Dihydroresveratrol | 58436-28-5 | >98.00% | |
Dihydroresveratrol is a major metabolite of resveratrol that is produced by animal-associated bacteria, including the gut microbiota. | ||||
| GC40301 | Tamoxifen N-oxide | 75504-34-6 | >98.00% | |
Tamoxifen is a selective estrogen receptor modulator that evokes tissue-dependent effects. | ||||
| GC40480 | α-Phenyl-α-(2-pyridyl)acetonitrile | 5005-36-7 | >98.00% | |
α-Phenyl-α-(2-pyridyl)thioacetamide, also known as antigastrin and SC-15396, is an inhibitor of gastric acid secretion. | ||||
| GC40529 | 7-hydroxy Warfarin | 17834-03-6 | >98.00% | |
7-hydroxy Warfarin is a metabolite of (-)-warfarin, which is a more potent vitamin K antagonist than (+)-warfarin. | ||||
| GC40616 | Des-4-fluorobenzyl Mosapride | 152013-26-8 | >96.00% | |
Des-4-fluorobenzyl Mosapride is the primary metabolite of mosapride. | ||||
| GC40627 | tetranor-Misoprostol | - | >95.00% | |
tetranor-Misoprostol is a metabolite of misoprostol. | ||||
| GC40675 | 2-deoxy-Artemisinin | 72826-63-2 | >98.00% | |
2-deoxy-Artemisinin is an inactive metabolite of the antimalarial agent artemisinin. | ||||
| GC40834 | cis-Entacapone | 145195-63-7 | >98.00% | |
cis-Entacapone is a metabolite of the catechol-O-methyltransferase (COMT) inhibitor entacapone. | ||||
| GC40852 | N-Demethylerythromycin A | 992-62-1 | >95.00% | |
N-Demethylerythromycin A is a metabolite of erythromycin. | ||||
| GC40879 | 4-hydroxy Solifenacin N-oxide | 2747991-39-3 | >95.00% | |
4-hydroxy Solifenacin N-oxide is an N-oxide form of 4-hydroxy solifenacin, the major metabolite of solifenacin . | ||||
| GC40968 | 21-hydroxy Eplerenone | 334678-67-0 | >98.00% | |
21-hydroxy Eplerenone is a major metabolite of the mineralocorticoid receptor antagonist eplerenone. | ||||