RN 1747 |
| Catalog No.GC15346 |
TRPV4 agonist
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1024448-59-6
Sample solution is provided at 25 µL, 10mM.
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RN-1747 is a selective transient receptor potential cation channel subfamily V member 4 (TRPV4) agonist, with EC50 values are 0.77 μM, 4.0 μM and 4.1 μM for hTRPV4, mTRPV4 and rTRPV4 respectively. RN-1747 also antagonizes TRPM8, with an IC50 of 4 μM[1].
References:
[1]. Vincent F, et al. Identification and characterization of novel TRPV4 modulators. Biochem Biophys Res Commun. 2009 Nov 20;389(3):490-4.
Average Rating: 5 (Based on Reviews and 27 reference(s) in Google Scholar.)
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