GLPBio

(S)-Bleximenib

Catalog No.: GC81619Purity:>96.00%Synonyms: (S)-JNJ-75276617; (S)-Menin-MLL inhibitor 24
COASDSData Sheet
(S)-Bleximenib (Compound 28) ((S)-JNJ-75276617) is an isoform of Bleximenib.

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(S)-Bleximenib
Cas No.: 2654081-27-1
1mgIn Stock
$115.00
1
5mgIn Stock
$348.00
1
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Citations

No citations are currently available for this product. Below are selected publications citing GlpBio products.
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    Nature
    641, 529–536 (2025)
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    628, 630–638 (2024)
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    632, 686–694 (2024)
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    618, 1017–1023 (2023)
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    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
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    Science
    388(6745) (2025)
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    387(6739) (2025)
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    387(6734) (2025)
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    Cell Research
    35, 97–116 (2025)
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    34, 683–706 (2024)
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    33, 273–287 (2023)
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    33, 546–561 (2023)
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    33, 904–922 (2023)
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    31, 1291–1307 (2021)

Description

(S)-Bleximenib (Compound 28) ((S)-JNJ-75276617) is an isoform of Bleximenib. (S)-Bleximenib shows an IC50 greater than 1 μM in the MEIS1 mRNA expression assay. (S)-Bleximenib can be used in the research of acute myeloid leukemia [1].

References:
[1]. Wei, et al. Substituted straight chain spiro derivatives. WO2021121327A1. WIPO (PCT). 2020-12-17.

Product Documents

Purity:>96.00%Appearance:An oil
COASDSData Sheet

Chemical Properties

CAS No.
2654081-27-1
Synonyms
(S)-JNJ-75276617; (S)-Menin-MLL inhibitor 24
Molecular Formula
C32H50FN7O3
Molecular Weight
599.78
Storage
Store at -20°C
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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