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(S)-Bleximenib (Synonyms: (S)-JNJ-75276617; (S)-Menin-MLL inhibitor 24)

Catalog No.GC81619 Copy One-Click Copy Product Info

(S)-Bleximenib (Compound 28) ((S)-JNJ-75276617) is an isoform of Bleximenib.

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(S)-Bleximenib Chemical Structure

Cas No.: 2654081-27-1

Size Price Stock Qty
1mg
$115.00
In stock
5mg
$348.00
In stock

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Sample solution is provided at 25 µL, 10mM.



Description of (S)-Bleximenib

(S)-Bleximenib (Compound 28) ((S)-JNJ-75276617) is an isoform of Bleximenib. (S)-Bleximenib shows an IC50 greater than 1 μM in the MEIS1 mRNA expression assay. (S)-Bleximenib can be used in the research of acute myeloid leukemia [1].

References:
[1]. Wei, et al. Substituted straight chain spiro derivatives. WO2021121327A1. WIPO (PCT). 2020-12-17.

Chemical Properties of (S)-Bleximenib

Cas No. 2654081-27-1 SDF
Synonyms (S)-JNJ-75276617; (S)-Menin-MLL inhibitor 24
Formula C32H50FN7O3 M.Wt 599.78
Solubility Storage Store at -20°C
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of (S)-Bleximenib

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1 mg 5 mg 10 mg
1 mM 1.6673 mL 8.3364 mL 16.6728 mL
5 mM 333.5 μL 1.6673 mL 3.3346 mL
10 mM 166.7 μL 833.6 μL 1.6673 mL
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In vivo Formulation Calculator (Clear solution) of (S)-Bleximenib

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

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Review for (S)-Bleximenib

Average Rating: 5 ★★★★★ (Based on Reviews and 30 reference(s) in Google Scholar.)

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