(S,R,S)-AHPC-Me-amide-C-O-PEG2-COOH is an E3 ligase ligand-linker conjugate. (S,R,S)-AHPC-Me-amide-C-O-PEG2-COOH can be used for synthesis of PROTACs [1] [2].
References:
[1]. Li Y, et al. Discovery of potent hypoxia-inducible factor-1α (HIF-1α) degraders by proteolysis targeting chimera (PROTAC). Bioorg Chem. 2024 Dec;153:107943.
[2]. Steven D. Knight. Compounds and compositions as fgfr3 degraders and uses thereof. WO2024137742A1. 2024-06-27.
References:
[1]. Li Y, et al. Discovery of potent hypoxia-inducible factor-1α (HIF-1α) degraders by proteolysis targeting chimera (PROTAC). Bioorg Chem. 2024 Dec;153:107943.
[2]. Steven D. Knight. Compounds and compositions as fgfr3 degraders and uses thereof. WO2024137742A1. 2024-06-27.
















