GLPBio

Selovoxolone

Catalog No.: GC79726Purity:>98.00%Synonyms: CKBA
COASDSData Sheet
Selovoxolone (CKBA), a derivative of AKBA is an inhibitor of acetyl-CoA carboxylase 1 ( ACC1 ), with an IC50 of 5.02 μM.

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Selovoxolone
Cas No.: 1786406-66-3
10mM (in 1mL DMSO)In Stock
$403.00
1
5mgIn Stock
$315.00
1
10mgIn Stock
$477.00
1
Tel: (909) 407-4943 / (909) 689-7124Email: sales@glpbio.com

Citations

No citations are currently available for this product. Below are selected publications citing GlpBio products.
  • Nature cover
    Nature
    641, 529–536 (2025)
  • Nature cover
    Nature
    628, 630–638 (2024)
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    Nature
    632, 686–694 (2024)
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    Nature
    618, 1017–1023 (2023)
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    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
  • Science cover
    Science
    388(6745) (2025)
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    Science
    387(6739) (2025)
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    Science
    387(6734) (2025)
  • Cell Research cover
    Cell Research
    35, 97–116 (2025)
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    Cell Research
    34, 683–706 (2024)
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    Cell Research
    33, 273–287 (2023)
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    Cell Research
    33, 546–561 (2023)
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    Cell Research
    33, 904–922 (2023)
  • Cell Research cover
    Cell Research
    31, 1291–1307 (2021)

Description

Selovoxolone (CKBA), a derivative of AKBA is an inhibitor of acetyl-CoA carboxylase 1 ( ACC1 ), with an IC50 of 5.02 μM. Selovoxolone inhibits the differentiation of Th17 cells and has IC50 values of 3.28 μM for mouse cells and 3.61 μM for human cells. Selovoxolone ointment significantly alleviates psoriasis-like inflammation in mice. Selovoxolone can be used for the study of psoriasis [1].

References:
[1]. Lou F, et al. Identification and pre-clinical investigation of 3-O-cyclohexanecarbonyl-11-keto-β-boswellic acid as a drug for external use to treat psoriasis. Br J Pharmacol. 2024 Apr;181(8):1290-1307.

Product Documents

Purity:>98.00%Appearance:A solid
COASDSData Sheet

Chemical Properties

CAS No.
1786406-66-3
Synonyms
CKBA
Molecular Formula
C37H56O5
Molecular Weight
580.84
Solubility
DMSO: 100 mg/mL (172.16 mM; Need ultrasonic)
Storage
Store at -20°C
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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