GLPBio

Sirtuin modulator 8

Catalog No.: GC84084Purity:>96.00%
COASDSData Sheet
Sirtuin modulator 8 is a sirtuin modulator that can activate Sirtuin activity.

Products are for research use only. Not for human use. We do not sell to patients.

Sirtuin modulator 8
Cas No.: 925437-38-3
500μgIn Stock
$302.00
1
Tel: (909) 407-4943 / (909) 689-7124Email: sales@glpbio.com

Citations

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    610, 366–372 (2022)
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    Cell
    187(9):2288-2304 (2024)
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    183(7):1867-1883 (2020)
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Description

Sirtuin modulator 8 is a sirtuin modulator that can activate Sirtuin activity. Sirtuin modulator 8 significantly downregulates the expression of monocyte chemoattractant protein-1 (MCP-1) and upregulates the expression of fibroblast growth factor 21 (FGF21). Sirtuin modulator 8 regulates the expression of inflammation- and metabolism-related genes, showing potential for studying metabolic diseases (such as diabetes, obesity ) and inflammatory diseases [1].

In Vitro, Sirtuin modulator 8 (Compound 2) (2 μM) causes a significant decrease in MCP-1 expression in a human leukocyte (WBC) model, indicating its potential to inhibit inflammatory responses[1].

References:
[1]. Olivier Boss, et al. Biomarkers of sirtuin activity and methods of use thereof.WO2008115518A2.US.2008-09-25

Product Documents

Purity:>96.00%Appearance:A solid
COASDSData Sheet

Chemical Properties

CAS No.
925437-38-3
Molecular Formula
C26H25N7OS
Molecular Weight
483.59
Storage
Store at -20°C
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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