GLPBio

Sorivudine

Catalog No.: GC39552Purity:>95.00%
COASDSData Sheet
Sorivudine (BV-araU) is an orally active synthetic pyrimidine nucleoside antimetabolite drug.

Products are for research use only. Not for human use. We do not sell to patients.

Sorivudine
Cas No.: 77181-69-2
10mM (in 1mL DMSO)In Stock
$148.00
1
5mgIn Stock
$135.00
1
10mgIn Stock
$213.00
1
25mgIn Stock
$389.00
1
50mgIn Stock
$649.00
1
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Description

Sorivudine (BV-araU) is an orally active synthetic pyrimidine nucleoside antimetabolite drug. Sorivudine derives its antiviral activity from selective conversion by a specific thymidine kinase present in certain DNA viruses to nucleotides, which can in turn interfere with viral DNA synthesis[1].

[1]. Diasio RB, et al. Sorivudine and 5-fluorouracil; a clinically significant drug-drug interaction due to inhibition of dihydropyrimidine dehydrogenase. Br J Clin Pharmacol. 1998 Jul;46(1):1-4. [2]. Whitley RJ, et al. Sorivudine: a potent inhibitor of varicella zoster virus replication.Adv Exp Med Biol. 1996;394:41-4.

Product Documents

Purity:>95.00%Appearance:A solid
COASDSData Sheet

Chemical Properties

CAS No.
77181-69-2
SMILES
O=C1NC(C(/C=C/Br)=CN1[C@H]2[C@H]([C@@H]([C@@H](CO)O2)O)O)=O
Molecular Formula
C11H13BrN2O6
Molecular Weight
349.13
Solubility
DMSO: 250 mg/mL (716.07 mM)
Storage
Store at -20°C
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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