5α,6α-Epoxysitosterol is a minor β-sitosterol oxidation product and 5,6-epoxy thermo-oxidation product of sitosterol [1] [2].
In Vitro, 5α,6α-Epoxysitosterol (5,6α-epoxysitosterol) is a minor thermal oxidation product generated from pure β-sitosterol at 180 °C[1]. 5α,6α-Epoxysitosterol is a minor thermal oxidation product formed from β-sitosterol in corn oil, lard and olive oil at 180 °C[1]. 5α,6α-Epoxysitosterol is a product formed by heating natural sitosterol in rapeseed oil[2].
References:
[1]. Xu G, Guan L, Sun J, et al.. Oxidation of cholesterol and beta-sitosterol and prevention by natural antioxidants. Journal of agricultural and food chemistry. 2009 Oct 14;57(19):9284-92.
[2]. Lampi AM, Juntunen L, Toivo J, et al.. Determination of thermo-oxidation products of plant sterols. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2002 Sep 25;777(1-2):83-92.
In Vitro, 5α,6α-Epoxysitosterol (5,6α-epoxysitosterol) is a minor thermal oxidation product generated from pure β-sitosterol at 180 °C[1]. 5α,6α-Epoxysitosterol is a minor thermal oxidation product formed from β-sitosterol in corn oil, lard and olive oil at 180 °C[1]. 5α,6α-Epoxysitosterol is a product formed by heating natural sitosterol in rapeseed oil[2].
References:
[1]. Xu G, Guan L, Sun J, et al.. Oxidation of cholesterol and beta-sitosterol and prevention by natural antioxidants. Journal of agricultural and food chemistry. 2009 Oct 14;57(19):9284-92.
[2]. Lampi AM, Juntunen L, Toivo J, et al.. Determination of thermo-oxidation products of plant sterols. Journal of chromatography. B, Analytical technologies in the biomedical and life sciences. 2002 Sep 25;777(1-2):83-92.