GLPBio

BVDU 5′-Triphosphate ammonium

Catalog No.: GC85007Purity:>98.00%Synonyms: (E)-5-(2-Bromovinyl)-dUTP ammonium; BVdUTP ammonium
COASDSData Sheet
BVDU 5′-Triphosphate ammonium is an antivirus agent with 5′-Triphosphate label, targeting viral DNA polymerase.

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BVDU 5′-Triphosphate ammonium
1mgIn Stock
$123.00
1
5mgIn Stock
$270.00
1
10mgIn Stock
$432.00
1
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Citas (Citations)

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    Nature
    641, 529–536 (2025)
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    628, 630–638 (2024)
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    632, 686–694 (2024)
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    618, 1017–1023 (2023)
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    610, 366–372 (2022)
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    Cell
    187(9):2288-2304 (2024)
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    Cell
    183(7):1867-1883 (2020)
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    388(6745) (2025)
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    387(6734) (2025)
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    35, 97–116 (2025)
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    34, 683–706 (2024)
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    33, 273–287 (2023)
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    33, 546–561 (2023)
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    33, 904–922 (2023)
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    31, 1291–1307 (2021)

Descripción (Description)

BVDU 5′-Triphosphate ammonium is an antivirus agent with 5′-Triphosphate label, targeting viral DNA polymerase. BVDU 5′-Triphosphate ammonium shows excellent selectivity against varicella-zoster virus ( VZV ) and herpes simplex virus type 1 ( HSV-1 ), due to a specific phosphorylation by the virus-encoded thymidine kinase.

References:
[1]. De Clercq E. Discovery and development of BVDU (brivudin) as a therapeutic for the treatment of herpes zoster. Biochem Pharmacol. 2004 Dec 15;68(12):2301-15.

Documentos del producto (Product Documents)

Purity:>98.00%Appearance:A solid
COASDSData Sheet

Propiedades químicas (Chemical Properties)

Sinónimos
(E)-5-(2-Bromovinyl)-dUTP ammonium; BVdUTP ammonium
Fórmula molecular
C11H19BrN3O14P3
Peso molecular
590.11
Solubilidad
H2O: 250 mg/mL (423.65 mM; Need ultrasonic)
Almacenamiento
Store at -20°C, stored under nitrogen, away from moisture
Condiciones de envío
Las muestras de evaluación se envían con acumuladores de frío. Los demás tamaños se envían a temperatura ambiente o, previa solicitud, con acumuladores de frío.

Calculadoras (Calculators)Molaridad / Dilución / Peso molecular / Conversión de unidades / Formulación in vivo / Solubilidad

g/mol

Reviews

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