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Cdk5i peptide

Catalog No.GC74324

Cdk5i peptide es un fragmento de péptido de 12 aminoácidos derivado de Cdk5.

Products are for research use only. Not for human use. We do not sell to patients.

Cdk5i peptide Chemical Structure

Cas No.: 2298317-00-5

Tamaño Precio Disponibilidad Cantidad
1 mg
45,00 $
Disponible
5 mg
113,00 $
Disponible
10 mg
180,00 $
Disponible

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Sample solution is provided at 25 µL, 10mM.

Description of Cdk5i peptide

Cdk5i peptide is a 12-amino acid peptide fragment derived from Cdk5. Cdk5i peptide is an inhibitor of Cdk5 peptide. Cdk5i peptide can be used in the stud y of neurodegenerative diseases.

References:
[1]. Pao PC, et al. A Cdk5-derived peptide inhibits Cdk5/p25 activity and improves neurodegenerative phenotypes. Proc Natl Acad Sci U S A. 2023 Apr 18;120(16):e2217864120.

Chemical Properties of Cdk5i peptide

Cas No. 2298317-00-5 SDF
Formula C60H94N18O15S M.Wt 1339.56
Solubility DMSO : 2 mg/mL (1.49 mM; Need ultrasonic) Storage Sealed storage, away from moisture
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of Cdk5i peptide

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 0.7465 mL 3.7326 mL 7.4651 mL
5 mM 0.1493 mL 0.7465 mL 1.493 mL
10 mM 0.0747 mL 0.3733 mL 0.7465 mL
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**When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / CoA (available online).

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In vivo Formulation Calculator (Clear solution) of Cdk5i peptide

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

Quality Control & SDS

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Average Rating: 5 ★★★★★ (Based on Reviews and 30 reference(s) in Google Scholar.)

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