HCV Protease
Read More about this categoryShow Less
Hepatitis C virus (HCV) protease is an enzyme, either viral or cellular, that catalyzes the hydrolysis of the long polyprotein precursor (approximately 3000 amino acids) encoded by HCV genome into at least ten individual proteins, including four structural proteins (C, E1, E2 and p7) and six nonstructural (NS) proteins (NS2, NS3, NS4A, NS4B, NS5A and NS5B). The commonly studied HCV proteases are two virally encode proteases involved in the viral replication of HCV, including HCV NS2/3 protease, a highly hydrophobic protease responsible for the cleavage of NS2 and NS3, and HCV NS3-4A serine protease, a covalent heterodimer responsible for cleavage at four sites of the HCV polyprotein.
Products Related to HCV Protease(37)
- GC14074NarlaprevirCAS: 865466-24-6Purity: >98.00%
Narlaprevir es un inhibidor muy selectivo que se toma por vía oral. Actúa contra la proteína no estructural 3 del virus de la hepatitis C, mejor dicho la NS3 del HCV, y presenta un valor K i de 6nM junto a un EC 90 de 40nM.
- GC17701Clemizole hydrochlorideCAS: 1163-36-6Purity: >99.50%
An antihistamine and TRPC5 channel blocker
- GC19165GlecaprevirCAS: 1365970-03-1Purity: >98.00%
Glecaprevir es un inhibidor de la proteasa NS3/4A del VHC novedoso, con valores de IC50 que van desde 3.5 hasta 11.3 nM.
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GC12057 | Daclatasvir (BMS-790052) | 1214735-16-6 | >98% | |
HCV NS5A inhibitor | ||||
| GC10155 | Vaniprevir | 923590-37-8 | >98% | |
| GC10832 | VX-222 (VCH-222, Lomibuvir) | 1026785-59-0 | >98% | |
An HCV polymerase inhibitor | ||||
| GC10930 | Balapiravir | 690270-29-2 | >98% | |
| GC10959 | Boceprevir | 394730-60-0 | >98.00% | |
An NS3/4A protease inhibitor | ||||
| GC11463 | MK-5172 sodium salt | 1425038-27-2 | >98% | |
| GC11840 | Ciluprevir (BILN-2061) | 300832-84-2 | >98% | |
Inhibitor of HCV NS3 protease | ||||
| GC12236 | Daclatasvir dihydrochloride | 1009119-65-6 | >99.50% | |
An NS5A inhibitor | ||||
| GC12299 | Telaprevir (VX-950) | 402957-28-2 | >98.00% | |
An HCV NS3/4A protease inhibitor | ||||
| GC12444 | Clemizole | 442-52-4 | >98% | |
An antihistamine and TRPC5 channel blocker | ||||
| GC12879 | Danoprevir (RG7227) | 850876-88-9 | >99.50% | |
An HCV NS3/4A protease inhibitor | ||||
| GC13312 | HZ-1157 | 1009734-33-1 | >98.50% | |
HZ-1157 inhibe la proteasa NS3/4A del VHC con una IC50 de 1,0 μmol/L. | ||||
| GC14074 | Narlaprevir | 865466-24-6 | >98.00% | |
Narlaprevir es un inhibidor muy selectivo que se toma por vía oral. Actúa contra la proteína no estructural 3 del virus de la hepatitis C, mejor dicho la NS3 del HCV, y presenta un valor K i de 6nM junto a un EC 90 de 40nM. | ||||
| GC14458 | Asunaprevir (BMS-650032) | 630420-16-5 | >99.50% | |
An HCV NS3/4A protease inhibitor | ||||
| GC14937 | Anguizole | 442666-98-0 | >99.50% | |
| GC15891 | Nesbuvir | 691852-58-1 | >98.50% | |
| GC16098 | MK-5172 hydrate | 1350462-55-3 | >99.00% | |
| GC16887 | Tegobuvir | 1000787-75-6 | >98.00% | |
A non-nucleoside inhibitor of HCV NS5B | ||||
| GC16901 | PSI-6206 | 863329-66-2 | >99.50% | |
An inactive derivative of a HCV NS5B inhibitor | ||||
| GC17114 | MK-5172 potassium salt | 1206524-86-8 | >99.00% | |
| GC17270 | Simeprevir | 923604-59-5 | >99.50% | |
A potent NS3/4A protease inhibitor | ||||
| GC17701 | Clemizole hydrochloride | 1163-36-6 | >99.50% | |
An antihistamine and TRPC5 channel blocker | ||||
| GC18004 | MK-5172 | 1350514-68-9 | >99.50% | |
MK-5172 es un inhibidor muy selectivo de la proteasa NS3/4a del virus de la hepatitis C. Funciona contra muchos genotipos y variantes resistentes a los fármacos. También frena la actividad de la proteasa SARS-CoV-2 3CL | ||||
| GC19165 | Glecaprevir | 1365970-03-1 | >98.00% | |
Glecaprevir es un inhibidor de la proteasa NS3/4A del VHC novedoso, con valores de IC50 que van desde 3.5 hasta 11.3 nM. | ||||