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Isochlortetracycline (Synonyms: 7-Chloroisotetracycline, Isoaureomycin)

Catalog No.GC18649 Copy One-Click Copy Product Info

Isochlortetracycline is an inactive alkaline degradation product of the broad-spectrum antibiotic chlortetracycline.

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Isochlortetracycline Chemical Structure

Cas No.: 514-53-4

Tamaño Precio Disponibilidad Cantidad
1mg
88,00 $
Disponible
5mg
339,00 $
Disponible
10mg
548,00 $
Disponible

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Sample solution is provided at 25 µL, 10mM.



Description of Isochlortetracycline

Isochlortetracycline is an inactive alkaline degradation product of the broad-spectrum antibiotic chlortetracycline. This molecule appears to be a product of in vivo chlortetracycline metabolism with epimerization rates exceeding >50%, and high levels can be detected in the yolks of eggs from chickens exposed to this antibiotic. Isochlortetracycline is used as a reference standard in chromatographic analyses of chlortetracycline and its metabolic derivatives.

Chemical Properties of Isochlortetracycline

Cas No. 514-53-4 SDF
Sinónimos 7-Chloroisotetracycline, Isoaureomycin
Chemical Name (4S,4aS,6S,8aS)-6-[(1S)-7-chloro-1,3-dihydro-4-hydroxy-1-methyl-3-oxo-1-isobenzofuranyl]-4-(dimethylamino)-1,4,4a,5,6,7,8,8a-octahydro-3,8a-dihydroxy-1,8-dioxo-2-naphthalenecarboxamide
Canonical SMILES O=C([C@@](C(C(C(N)=O)=C(O)[C@H]1N(C)C)=O)(O)[C@@]1([H])C2)C[C@@]2([H])[C@]3(C)OC(C4=C3C(Cl)=CC=C4O)=O
Formula C22H23ClN2O8 M.Wt 478.9
Solubility DMF: soluble,DMSO: soluble,Ethanol: soluble,Methanol: soluble Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of Isochlortetracycline

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 2.0881 mL 10.4406 mL 20.8812 mL
5 mM 417.6 μL 2.0881 mL 4.1762 mL
10 mM 208.8 μL 1.0441 mL 2.0881 mL
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**When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and MSDS / CoA (available online).

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In vivo Formulation Calculator (Clear solution) of Isochlortetracycline

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % saline
%DMSO %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

Quality Control & SDS

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Review for Isochlortetracycline

Average Rating: 5 ★★★★★ (Based on Reviews and 10 reference(s) in Google Scholar.)

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