JWH 175 is a synthetic cannabinoid (CB) that potently activates the central CB1 receptor (Ki = 22 nM).[1] As a naphthylmethylindole, it is structurally related to JWH 018. The properties of this compound at the peripheral CB2 receptor or in vivo have not been characterized. This product is intended for forensic and research purposes.
Reference:
[1]. Huffman, J.W., Mabon, R., Wu, M.J., et al. 3-indolyl-1-naphthylmethanes: New cannabimimetic indoles provide evidence for aromatic stacking interactions with the CB1 cannabinoid receptor. Bioorganic & Medicinal Chemistry 11, 539-549 (2003).