GLPBio

KRAS G12D inhibitor 10

Catalog No.: GC83345Purity:>88.50%
COASDSData Sheet
KRAS G12D inhibitor 10 is a potent inhibitor of KRAS G12D.

Los productos son exclusivamente para uso en investigación. No aptos para uso humano. No vendemos a pacientes.

KRAS G12D inhibitor 10
Cas No.: 2648551-54-4
10mM (in 1mL DMSO)In Stock
$416.00
1
1mgIn Stock
$122.00
1
5mgIn Stock
$306.00
1
10mgIn Stock
$497.00
1
Tel: (909) 407-4943 / (909) 689-7124Email: sales@glpbio.com

Citas (Citations)

Actualmente no hay citas disponibles para este producto. A continuación se muestran publicaciones seleccionadas que citan productos GlpBio.
  • Nature cover
    Nature
    641, 529–536 (2025)
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    Nature
    628, 630–638 (2024)
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    Nature
    632, 686–694 (2024)
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    Nature
    618, 1017–1023 (2023)
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    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
  • Science cover
    Science
    388(6745) (2025)
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    Science
    387(6739) (2025)
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    Science
    387(6734) (2025)
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    Cell Research
    35, 97–116 (2025)
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    Cell Research
    34, 683–706 (2024)
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    Cell Research
    33, 273–287 (2023)
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    Cell Research
    33, 546–561 (2023)
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    Cell Research
    33, 904–922 (2023)
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    Cell Research
    31, 1291–1307 (2021)

Descripción (Description)

KRAS G12D inhibitor 10 is a potent inhibitor of KRAS G12D. The Ras family of proteins is an important intracellular signaling molecule that plays an important role in growth and development. KRAS G12D inhibitor 10 has the potential for the research of KRAS G12D-mediated cancer (extracted from patent WO2021108683A1, compound 34) [1].

References:
[1]. Jennifer PITZEN, et al. Covalent ras inhibitors and uses thereof. Patent WO2021108683A1.

Documentos del producto (Product Documents)

Purity:>88.50%Appearance:A solid
COASDSData Sheet

Propiedades químicas (Chemical Properties)

N.º CAS
2648551-54-4
Fórmula molecular
C33H41ClN8O2
Peso molecular
617.18
Solubilidad
DMSO: 100 mg/mL (162.03 mM; Need ultrasonic)
Almacenamiento
Store at -20°C
Condiciones de envío
Las muestras de evaluación se envían con acumuladores de frío. Los demás tamaños se envían a temperatura ambiente o, previa solicitud, con acumuladores de frío.

Calculadoras (Calculators)Molaridad / Dilución / Peso molecular / Conversión de unidades / Formulación in vivo / Solubilidad

g/mol

Reviews

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