GLPBio

TRP Channel

TRP (transient receptor potential) channels are a family of cation channels that sense various external and celluar signals such as mechanical stress, temperature, cellular messengers and exogenous chemicals. It is implicated in vascular tone , neurological disorders, kidney diseases, hypomagnesemia and hypocalcemia etc.

Products Related to TRP Channel(184)

  • GC79528 structure
    GC79528ZA18
    CAS: 2696407-32-4
    Purity: >99.50%

    ZA18 is a selective TRPM2 channel inhibitor, with an IC 50 value of 6.2 μM.

  • GC79529 structure
    GC79529TRPC3 agonist-1
    CAS: 1589567-51-0
    Purity: >99.50%

    TRPC3 agonist-1 (compound 4n) is a selective and competitive TRPC3 channel agonist.

  • GC79530 structure
    GC79530Trpvicin
    CAS: 2019994-90-0
    Purity: >98.00%

    Trpvicin is a potent and subtype-selective TRPV3 inhibitor with IC 50 s of 0.41 and 0.22 μM for hTRPV3-WT and hTRPV3-G573S mutant, respectively.

  • GC79531 structure
    GC79531L-R4W2 acetate
    Purity: >98.00%

    L-R4W2 acetate is a potent antagonist of vanilloid receptor 1 (VR1, TRPV1 ), with an IC 50 of 0.1 μM.

  • GC79532 structure
    GC79532HKC54
    Purity: >98%

    HKC54 is a selective TRPV2 antagonist with an IC 50 of 0.4 μM.

  • GC79533 structure
    GC79533FP802
    CAS: 61694-81-3
    Purity: >98%

    FP802 is an orally active potent TwinF interface inhibitor that disrupts and detoxifies the NMDAR/TRPM4 death complex.

  • GC79534 structure
    GC79534FP802 dihydrochloride
    CAS: 2490401-57-3
    Purity: >99.50%

    FP802 dihydrochloride is an orally active potent TwinF interface inhibitor that disrupts and detoxifies the NMDAR/TRPM4 death complex.

  • GC79781 structure
    GC797818-Br-ADPR disodium
    Purity: >98.00%

    8-Br-ADPR disodium (8-Bromoadenosine-5'-O-diphosphoribose) is a TRPM2 inhibitor and ADPR signaling pathway antagonist.

  • GC80473 structure
    GC80473Pregnenolone-d 6
    Purity: >98%

    Pregnenolone -d 6 (3β-Hydroxy-5-pregnen-20-one-d 6 ) is the deuterium labeled Pregnenolone [1] . Pregnenolone (3β-Hydroxy-5-pregnen-20-one) is a powerful neurosteroid, the main precursor of various steroid hormones including steroid ketones.

  • GC80843 structure
    GC80843Acoltremon-d 3
    Purity: >99.50%

    Acoltremon -d 3 (WS-12-d 3 ) is the deuterium labeled Acoltremon.

  • GC80865 structure
    GC80865Anandamide- 15 N
    Purity: >99.50%

    Anandamide - 15 N (AEA- 15 N) is the 15 N-labeled Anandamide.

  • GC81683 structure
    GC81683AM9053
    CAS: 157469-21-1
    Purity: >98.00%

    AM9053 is a selective, effective and slowly reversible inhibitor of N-acyl ethanolamine acid amidease ( NAAA ) ( IC 50 = 30 nM).

  • GC81725 structure
    GC81725TRPV1 antagonist 10
    CAS: 896584-55-7
    Purity: >98.50%

    TRPV1 antagonist 10 is an orally active and potent TRPV1 antagonist ( IC 50 = 33.06 nM), moderate to weak URAT1 ( IC 50 = 22.51 μM) and GLUT9 (60.25% at 50 μM) inhibitor.

  • GN10437 structure
    GN10437Imperatorin
    CAS: 482-44-0
    Purity: >98.00%
  • GN10792 structure
    GN10792Caffeic acid
    CAS: 331-39-5
    Purity: >98.50%

    Caffeic acid is a hydroxycinnamic acid polyphenol compound with antioxidant activity. Caffeic acid is an inhibitor of TRPV1 ion channel and 5-lipoxygenase.

  • GC12769 structure
    GC12769Nonivamide
    CAS: 2444-46-4
    Purity: >98.00%

    Nonivamide es un agonista <b, que muestra un valor 4d-EC50 de 5,1 mg/L en pruebas de toxicidad est&Aacute;tica.