p38
p38 (p38 mitogen-activated protein kinases) are serine/threonine kinases that activated by environmental stress and proinflammatory cydtokines. They mediates cell growth, differentiation, transcrption and development.
Products Related to p38(158)
- GC817573-Ethoxy-5,6-dibromosalicylaldehydeCAS: 20041-64-9Purity: >99.50%
3-Ethoxy-5,6-dibromosalicylaldehyde is an IRE1/ERN1 inhibitor, with an IC 50 of 0.12 μM, a K i of 71-88 nM, and a K d of 100 nM against the ribonuclease activity of hIRE1α, as well as an IC 50 of 4.8 μM against yeast Ire1.
- GC81771RANKL-IN-1 formatePurity: >99.50%
RANKL-IN-1 formate is a selective receptor activator of nuclear factor-κB ligand inhibitor ligand ( RANKL ) inhibitor with a K D value of 7.6 μM.
- GC81827Buforin IIb TFAPurity: >98.00%
Buforin IIb TFA (BF2-B TFA) is an anticancer peptide, as well as an Antibacterial and Antifungal agent.
- GF10446Keyhole limpet hemocyaninCAS: 9013-72-3Purity: ≥85.00%
Keyhole limpet hemocyanin lleva cobre y es muy inmunogénica. Viene del molusco marino Megathura crenulata
- GN10248HesperitinCAS: 520-33-2Purity: >98.50%
Hesperetin is the aglycone form of hesperidin, a citrus bioflavonoid.
- GC13001SB 203580 hydrochlorideCAS: 869185-85-3Purity: >98.00%
El clorhidrato de adezmapimod (SB 203580) es un inhibidor de p38 MAPK selectivo y competitivo con ATP con IC50 de 50 nM y 500 nM para SAPK2a/p38 y SAPK2b/p38β2, respectivamente.
- GC13968SB202190 (FHPI)CAS: 152121-30-7Purity: >99.00%
SB202190 (FHPI) es un inhibidor selectivo de la p38 MAP quinasa con IC50s de 50 nM y 100 nM para p38α y p38β2, respectivamente.
- GC13717LosmapimodCAS: 585543-15-3Purity: >98.00%
Losmapimod (GSK-AHAB) es un inhibidor selectivo, potente y activo por vÍa oral de p38 MAPK con pKis de 8,1 y 7,6 para p38α y p38β, respectivamente.
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GC81460 | BTX-6654 formate | - | >98.50% | |
BTX-6654 formate is a SOS1 PROTAC degrader. | ||||
| GC81684 | CK37 | 1001478-90-5 | >98.00% | |
CK37 is a competitive choline kinase-α inhibitor. | ||||
| GC81757 | 3-Ethoxy-5,6-dibromosalicylaldehyde | 20041-64-9 | >99.50% | |
3-Ethoxy-5,6-dibromosalicylaldehyde is an IRE1/ERN1 inhibitor, with an IC 50 of 0.12 μM, a K i of 71-88 nM, and a K d of 100 nM against the ribonuclease activity of hIRE1α, as well as an IC 50 of 4.8 μM against yeast Ire1. | ||||
| GC81771 | RANKL-IN-1 formate | - | >99.50% | |
RANKL-IN-1 formate is a selective receptor activator of nuclear factor-κB ligand inhibitor ligand ( RANKL ) inhibitor with a K D value of 7.6 μM. | ||||
| GC81827 | Buforin IIb TFA | - | >98.00% | |
Buforin IIb TFA (BF2-B TFA) is an anticancer peptide, as well as an Antibacterial and Antifungal agent. | ||||
| GF10446 | Keyhole limpet hemocyanin | 9013-72-3 | ≥85.00% | |
Keyhole limpet hemocyanin lleva cobre y es muy inmunogénica. Viene del molusco marino Megathura crenulata | ||||
| GF11023 | Hecubine | 62874-52-6 | >98.00% | |
Hecubine is a natural aspidosperma-type alkaloid found in E. officinalis , with anti-neuroinflammation properties. | ||||
| GN10248 | Hesperitin | 520-33-2 | >98.50% | |
Hesperetin is the aglycone form of hesperidin, a citrus bioflavonoid. | ||||
| GN10409 | cor-nuside | 131189-57-6 | >98.50% | |
| GN10590 | Bakuchiol | 10309-37-2 | >98.00% | |
| GN10784 | Rhoifolin | 17306-46-6 | >98.00% | |
| GC13001 | SB 203580 hydrochloride | 869185-85-3 | >98.00% | |
El clorhidrato de adezmapimod (SB 203580) es un inhibidor de p38 MAPK selectivo y competitivo con ATP con IC50 de 50 nM y 500 nM para SAPK2a/p38 y SAPK2b/p38β2, respectivamente. | ||||
| GC13968 | SB202190 (FHPI) | 152121-30-7 | >99.00% | |
SB202190 (FHPI) es un inhibidor selectivo de la p38 MAP quinasa con IC50s de 50 nM y 100 nM para p38α y p38β2, respectivamente. | ||||
| GC13717 | Losmapimod | 585543-15-3 | >98.00% | |
Losmapimod (GSK-AHAB) es un inhibidor selectivo, potente y activo por vÍa oral de p38 MAPK con pKis de 8,1 y 7,6 para p38α y p38β, respectivamente. | ||||