GLPBio

Phospholipase

Phospholipases are enzymes that catalyze the hydrolysis of phospholipids into fatty acids and other lipid mediators. It plays a variety of roles in tumorgenesis , inflammation and brain disorders etc.

Products Related to Phospholipase(136)

  • GC43670 structure
    GC43670FKGK 11
    CAS: 1071000-98-0
    Purity: >98.00%

    FKGK 11 es un inhibidor potente y selectivo de GVIA iPLA2 (Grupo VIA de fosfolipasa A2 independiente del calcio).

  • GC43671 structure
    GC43671FKGK 18
    CAS: 1071001-09-6
    Purity: >95.00%

    FKGK 18 es un inhibidor selectivo de la fosfolipasa A2 independiente del calcio del grupo VIA (GVIA iPLA2).

  • GC43695 structure
    GC43695Folipastatin
    CAS: 139959-71-0
    Purity: >95.00%

    La folipastatina es un potente inhibidor de la fosfolipasa A2 con una IC50 de 39 μM.

  • GC43701 structure
    GC43701FTY720 phenoxy-biotin
    Purity: >95.00%

    FTY720 es un modulador inmunológico que regula a la baja los receptores de esfingosina-1-fosfato (S1P), mejora la actividad del transportador de esfingosina ABCB1 y el transportador de leucotrienos C4 ABCC1 e inhibe la actividad de fosfolipasa A2 citosólica.

  • GC43756 structure
    GC43756GK187
    CAS: 1071001-50-7
    Purity: >95.00%

    GK187 es un inhibidor potente y selectivo de la fosfolipasa A2 independiente del calcio del grupo VIA (GVIA iPLA2) con un valor XI(50) de 0,0001.

  • GC43812 structure
    GC43812HEPC
    CAS: 60793-01-3
    Purity: >95.00%

    Thioester analogs of glycerophospholipids, in combination with Ellman's reagent, are convenient colorimetric substrates for the measurement of phospholipase activity.

  • GC43815 structure
    GC43815Heptanoyl thio-PC
    Purity: >98.00%

    Thioester analogs of glycerophospholipids, in combination with Ellman's reagent, are convenient colorimetric substrates for the measurement of phospholipase (PL) activity.

  • GC44222 structure
    GC44222ML-298
    CAS: 1426916-02-0
    Purity: >98.00%

    ML298 es un inhibidor potente y selectivo de la fosfolipasa D2 (PLD2) con una IC50 de 355 nM. ML298 disminuye la migraciÓn invasiva en células de glioblastoma U87-MG.

  • GC44223 structure
    GC44223ML-299
    CAS: 1426916-00-8
    Purity: >95.00%

    ML-299 es un modulador alostérico selectivo y un inhibidor dual de las fosfolipasas D1 y D2 (los valores de IC50 son 6 y 12 nM, respectivamente). ML-299 disminuye la migración invasiva en células de glioblastoma U87-MG.

  • GC44549 structure
    GC44549Palmitoyl thio-PC
    CAS: 113881-60-0
    Purity: >98.00%

    Thioester analogs of glycerophospholipids, in combination with Ellman's reagent, are convenient colorimetric substrates for the measurement of phospholipase (PL) activity.

  • GC44661 structure
    GC44661PLC thio-PIP2 (sodium salt)
    Purity: >98.00%

    Phospholipase C (PLC) catalyzes the hydrolysis of phosphatidylinositol (4,5) bisphosphate (PIP2) on the cytoplasmic side of the cell membrane to yield diacylglycerol and inositol-1,4,5-triphosphate (IP3).

  • GC44664 structure
    GC44664p-Nitrophenylphosphorylcholine
    CAS: 21064-69-7
    Purity: >99.50%

    p-Nitrophenylphosphorylcholine es un sustrato cromogénico sintético comúnmente utilizado en la detección colorimétrica de la fosfolipasa C y las actividades relacionadas con la fosfodiesterasa

  • GC44764 structure
    GC44764PtdIns-(4,5)-P2 (1,2-dipalmitoyl) (ammonium salt)
    Purity: >98.00%

    The phosphatidylinositol phosphates represent a small percentage of total membrane phospholipids.

  • GC44794 structure
    GC44794Pyrrophenone
    CAS: 341973-06-6
    Purity: >99.50%

    La pirrofenona es un inhibidor potente y especÍfico de la fosfolipasa A2α citosÓlica (cPLA2α) con un valor IC50 de 4,2 nM.

  • GC44943 structure
    GC44943sPLA2 Inhibitor
    CAS: 393569-31-8
    Purity: >95.00%

    El inhibidor de sPLA2, un derivado de D-tirosina, es un potente inhibidor de la fosfolipasa A2 secretora (sPLA2) activo por vÍa oral con una IC50 de 29 nM para la isoforma IIa de PLA2 secretora no pancreÁtica humana (hnpsPLA2-IIa).

  • GC45618 structure
    GC45618(±)-trans-GK563
    CAS: 2351820-19-2
    Purity: >94.00%

    A GVIA iPLA 2 inhibitor

  • GC45995 structure
    GC45995DO264
    CAS: 2301866-59-9
    Purity: >98.50%

    An ABHD12 inhibitor

  • GC46342 structure
    GC46342(R)-Bromoenol lactone-d7
    Purity: >99.00%

    A neuropeptide with diverse biological activities

  • GC46350 structure
    GC46350(S)-Bromoenol lactone-d7
    CAS: 478288-94-7
    Purity: >99.00%

    A neuropeptide with diverse biological activities

  • GC46352 structure
    GC46352(S)-DO271
    CAS: 2301865-01-8
    Purity: >98.00%

    An inactive control for DO264

  • GC46494 structure
    GC464941-Stearoyl-2-Arachidonoyl-d11-sn-glycero-3-PC
    Purity: >99.00%

    A neuropeptide with diverse biological activities

  • GC46761 structure
    GC467619-Oxononanoic Acid
    CAS: 2553-17-5
    Purity: >98.00%

    An oxidized fatty acid

  • GC46955 structure
    GC46955Bromoenol lactone-d7
    Purity: >99.00%

    A neuropeptide with diverse biological activities

  • GC47049 structure
    GC47049CAY10641
    CAS: 1233706-89-2
    Purity: >98.00%

    An inactive alcohol derivative of a highly potent cPLA 2 inhibitor