Obesity, Appetite Control & Diabetes
Obesity, Appetite Control & Diabetes
Satiety, appetite, and craving are CNS drives, whereas metabolism and energy utilization are peripheral endocrine actions.
Stephen M. Stahl, M.D., Ph.D. read more
Research Areas
Products Related to Obesity, Appetite Control & Diabetes(354)
- GC44518Osteocalcin (1-49) (human) (trifluoroacetate salt)CAS: 136461-80-8Purity: >95.00%
Osteocalcin (1-49) is a non-collagenous peptide that is secreted by osteoblasts and odontoblasts and comprises 1-2% of the total protein in bone.
- GC44524Oxyntomodulin (bovine, porcine) (trifluoroacetate salt)Purity: >95.00%
Oxyntomodulin, also known as glucagon-37, is a 37-amino acid peptide produced in bovine and porcine gut.
- GC44544Palmitoleic Acid (sodium salt)CAS: 6610-24-8Purity: >95.00%
Palmitoleic acid is an ω-7 monounsaturated fatty acid that is a common constituent of the triglycerides of human adipose tissue.
- GC44598Peptide YY (human) (trifluoroacetate salt)Purity: >95.00%
Peptide YY (human) (trifluoroacetate salt) is a peptide hormone secreted by intestinal L cells.
- GC44645Pioglitazone (potassium salt)CAS: 1266523-09-4Purity: >98.00%
La pioglitazona (U 72107) potÁsica es un PPARγ activo por vÍa oral y selectivo; (receptor activado por proliferador de peroxisomas) agonista con uniÓn de alta afinidad al PPARγ dominio de uniÓn al ligando con EC50 de 0,93 μM y 0,99 μM para PPARγ humano y de ratÓn, respectivamente.
- GC44660PlatensimycinCAS: 835876-32-9Purity: >95.00%
Platensimycin (PTM) is an antibiotic produced by S.
- GC44775PTP1B InhibitorCAS: 765317-72-4Purity: >98.00%
PTP1B Inhibitor es un inhibidor alostérico no competitivo de la proteÍna tirosina fosfatasa PTP1B, con un IC50 de 8 μM.
- GC44811Remogliflozin etabonateCAS: 442201-24-3Purity: >99.00%
El etabonato de remogliflozina (GSK189075) es un inhibidor del cotransportador de sodio y glucosa (SGLT2) activo por vÍa oral, selectivo y de baja afinidad con valores de Ki de 1,95 μM, 2,14 μM, 43,1 μM, 8,57 μM para hSGLT2, rSGLT2, hSGLT1, rSGLT1, respectivamente.
- GC44851Rosiglitazone (potassium salt)CAS: 316371-84-3Purity: >98.00%
La rosiglitazona (BRL 49653) potÁsica es un PPARγ selectivo activo por vÍa oral; agonista (EC50: 60 nM, Kd: 40 nM).
- GC44895Sitagliptin N-Sulfate (sodium salt)CAS: 2470126-25-9Purity: >95.00%
Sitagliptin N-sulfate is a phase II metabolite of the dipeptidyl peptidase 4 (DPP-4) inhibitor (-)-sitagliptin.
- GC44914Somatostatin-14 (acetate)CAS: 54472-66-1Purity: >98.00%
Somatostatin-14 is a natural cyclic peptide hormone derived from the preprohormone, somatostatin.
- GC45139Vapreotide (trifluoroacetate salt)Purity: >95.00%
Vapreotide is a peptide neurokinin-1 receptor (NK1) antagonist and analog of somatostatin (IC50 = 330 nM in a radioligand binding assay).
- GC45144Vildagliptin carboxylic acid metabolite (trifluoroacetate salt)CAS: 565453-41-0Purity: >98.00%
Vildagliptin carboxylic acid metabolite is the major metabolite of the dipeptidyl peptidase 4 (DPP-4) inhibitor vildagliptin in humans.
- GC45186ZLN005 (hydrochloride)Purity: >98.00%
Peroxisome proliferator-activated receptor-γ coactivator-1α (PGC-1α) is a tissue-specific and inducible transcriptional coactivator for several nuclear receptors and plays a key role in energy metabolism, hepatic gluconeogenesis, and cholesterol homoeostasis.
- GC45252(-)-Sitagliptin Carbamoyl GlucuronideCAS: 940002-59-5Purity: >90.00%
(-)-Sitagliptin carbamoyl glucuronide is a minor phase II metabolite of the dipeptidyl peptidase 4 (DPP-4) inhibitor (-)-sitagliptin.
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GC44518 | Osteocalcin (1-49) (human) (trifluoroacetate salt) | 136461-80-8 | >95.00% | |
Osteocalcin (1-49) is a non-collagenous peptide that is secreted by osteoblasts and odontoblasts and comprises 1-2% of the total protein in bone. | ||||
| GC44524 | Oxyntomodulin (bovine, porcine) (trifluoroacetate salt) | - | >95.00% | |
Oxyntomodulin, also known as glucagon-37, is a 37-amino acid peptide produced in bovine and porcine gut. | ||||
| GC44529 | P053 | 2748196-63-4 | >97.00% | |
P053 es un inhibidor potente, no competitivo y selectivo de la ceramida sintasa 1 (CerS1) con una IC50 de 0,5μM. | ||||
| GC44544 | Palmitoleic Acid (sodium salt) | 6610-24-8 | >95.00% | |
Palmitoleic acid is an ω-7 monounsaturated fatty acid that is a common constituent of the triglycerides of human adipose tissue. | ||||
| GC44598 | Peptide YY (human) (trifluoroacetate salt) | - | >95.00% | |
Peptide YY (human) (trifluoroacetate salt) is a peptide hormone secreted by intestinal L cells. | ||||
| GC44645 | Pioglitazone (potassium salt) | 1266523-09-4 | >98.00% | |
La pioglitazona (U 72107) potÁsica es un PPARγ activo por vÍa oral y selectivo; (receptor activado por proliferador de peroxisomas) agonista con uniÓn de alta afinidad al PPARγ dominio de uniÓn al ligando con EC50 de 0,93 μM y 0,99 μM para PPARγ humano y de ratÓn, respectivamente. | ||||
| GC44660 | Platensimycin | 835876-32-9 | >95.00% | |
Platensimycin (PTM) is an antibiotic produced by S. | ||||
| GC44775 | PTP1B Inhibitor | 765317-72-4 | >98.00% | |
PTP1B Inhibitor es un inhibidor alostérico no competitivo de la proteÍna tirosina fosfatasa PTP1B, con un IC50 de 8 μM. | ||||
| GC44811 | Remogliflozin etabonate | 442201-24-3 | >99.00% | |
El etabonato de remogliflozina (GSK189075) es un inhibidor del cotransportador de sodio y glucosa (SGLT2) activo por vÍa oral, selectivo y de baja afinidad con valores de Ki de 1,95 μM, 2,14 μM, 43,1 μM, 8,57 μM para hSGLT2, rSGLT2, hSGLT1, rSGLT1, respectivamente. | ||||
| GC44851 | Rosiglitazone (potassium salt) | 316371-84-3 | >98.00% | |
La rosiglitazona (BRL 49653) potÁsica es un PPARγ selectivo activo por vÍa oral; agonista (EC50: 60 nM, Kd: 40 nM). | ||||
| GC44895 | Sitagliptin N-Sulfate (sodium salt) | 2470126-25-9 | >95.00% | |
Sitagliptin N-sulfate is a phase II metabolite of the dipeptidyl peptidase 4 (DPP-4) inhibitor (-)-sitagliptin. | ||||
| GC44914 | Somatostatin-14 (acetate) | 54472-66-1 | >98.00% | |
Somatostatin-14 is a natural cyclic peptide hormone derived from the preprohormone, somatostatin. | ||||
| GC44954 | Stevioside (hydrate) | - | >95.00% | |
Stevioside is a natural non-caloric sweetener. | ||||
| GC45139 | Vapreotide (trifluoroacetate salt) | - | >95.00% | |
Vapreotide is a peptide neurokinin-1 receptor (NK1) antagonist and analog of somatostatin (IC50 = 330 nM in a radioligand binding assay). | ||||
| GC45144 | Vildagliptin carboxylic acid metabolite (trifluoroacetate salt) | 565453-41-0 | >98.00% | |
Vildagliptin carboxylic acid metabolite is the major metabolite of the dipeptidyl peptidase 4 (DPP-4) inhibitor vildagliptin in humans. | ||||
| GC45164 | WWL229 | 1338575-28-2 | >98.00% | |
WWL229 es un inhibidor selectivo de la carboxilesterasa 3 (Ces3) con una IC50 de 1,94 μM. | ||||
| GC45186 | ZLN005 (hydrochloride) | - | >98.00% | |
Peroxisome proliferator-activated receptor-γ coactivator-1α (PGC-1α) is a tissue-specific and inducible transcriptional coactivator for several nuclear receptors and plays a key role in energy metabolism, hepatic gluconeogenesis, and cholesterol homoeostasis. | ||||
| GC45252 | (-)-Sitagliptin Carbamoyl Glucuronide | 940002-59-5 | >90.00% | |
(-)-Sitagliptin carbamoyl glucuronide is a minor phase II metabolite of the dipeptidyl peptidase 4 (DPP-4) inhibitor (-)-sitagliptin. | ||||
| GC45277 | (±)-Camphene | 79-92-5 | >99.50% | |
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| GC45315 | 1-Palmitoyl-d9-2,3-Dipalmitoyl-sn-glycerol | 2738376-70-8 | >99.00% | |
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| GC45320 | 1-Stearoyl-3-Oleoyl-rac-glycerol | 18266-27-8 | >98.00% | |
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| GC45379 | Alloxan (hydrate) | 2244-11-3 | >98.00% | |
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| GC45490 | Kisspeptin-54 (human) (trifluoroacetate salt) | - | >95.00% | |
| ||||
| GC45506 | MD001 | 2254605-76-8 | >90.00% | |
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