FGFR
FGFRs (fibroblast growth factor receptors) are transmembrane tyrosine kinase receptor. It is involved in carcinogenesis and plays an important role in cell differentiation, survival and proliferation etc.
Products Related to FGFR(109)
- GC73852Infigratinib-BocCAS: 2504949-83-9Purity: >98.00%
Infigratinib-Boc es un derivado del Infigratinib que contiene un grupo Boc (t-Butyloxy carbonyl).
- GC74365VSPPLTLGQLLSCAS: 1206896-24-3Purity: >98.00%
VSPPLTLGQLLS es un pequeño inhibidor del péptido FGFR3, el péptido P3, inhila la fosforilación del FGFR3.
- GC813192,4,3',4',6'-Penta-O-(3-methylbutanoyl)sucroseCAS: 150302-84-4Purity: >98%
2,4,3',4',6'-Penta-O-(3-methylbutanoyl)sucrose is an FGFR3 and BRAF binder, and is an isovaleryl sucrose ester that can be found in Atractylodes japonica.
- GC81325VEGFR2-IN-84CAS: 861877-12-5Purity: >98%
VEGFR2-IN-84 is an orally active, multi-targeted tyrosine kinase inhibitor based on a naphthalene ring scaffold.
- GC81329TCB-32 hydrochlorideCAS: 169764-95-8Purity: >97.50%
TCB-32 (Compound I-1) hydrochloride is a FGFR1 agonist with an EC 50 of 0.88 μM.
- GN10527FormononetinCAS: 485-72-3Purity: >99.50%
Formononetin es un potente inhibidor de FGFR2 con un IC50 de 4.3μM. La formononetina inhibe de manera eficaz la angiogénesis y el crecimiento tumoral.
- GN10540Fumalic acidCAS: 1135-24-6Purity: >99.00%
A phenol with diverse biological activities.Natural product, extracted from ligusticum chuanxiong.
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GC73852 | Infigratinib-Boc | 2504949-83-9 | >98.00% | |
Infigratinib-Boc es un derivado del Infigratinib que contiene un grupo Boc (t-Butyloxy carbonyl). | ||||
| GC73947 | CEP-11981 | 856691-93-5 | >99.00% | |
(ESK981) BOL 303213X) es un inhibide la tirosina cinasa (TKI) activo por vía oral, que puede atacar a TIE2, VEGFR1-3 y FGFR1, y tiene potenciales efectos antitumorales y antiangigénicos. | ||||
| GC74046 | BR-cpd7 | - | >98.00% | |
BR-cpd7 es un degrador PROTAC para el receptor del factor de crecimiento de fibroblafgfr1/2 con DC50 de 10 nM. | ||||
| GC74365 | VSPPLTLGQLLS | 1206896-24-3 | >98.00% | |
VSPPLTLGQLLS es un pequeño inhibidor del péptido FGFR3, el péptido P3, inhila la fosforilación del FGFR3. | ||||
| GC79483 | MD-3-A45 | 2314337-87-4 | >98.00% | |
MD-3-A45 is an inhibitor of fibroblast growth factor 23 ( FGF-23 ). | ||||
| GC81314 | OM-RCA-01 | - | >99.00% | |
OM-RCA-01 is an anti- FGFR1 monoclonal antibody with a K d of 1.59 nM for human FGFR1. | ||||
| GC81319 | 2,4,3',4',6'-Penta-O-(3-methylbutanoyl)sucrose | 150302-84-4 | >98% | |
2,4,3',4',6'-Penta-O-(3-methylbutanoyl)sucrose is an FGFR3 and BRAF binder, and is an isovaleryl sucrose ester that can be found in Atractylodes japonica. | ||||
| GC81324 | FGF7p | 2758194-43-1 | >99.00% | |
FGF7p is a small molecule peptide and a potential bladder protector. | ||||
| GC81325 | VEGFR2-IN-84 | 861877-12-5 | >98% | |
VEGFR2-IN-84 is an orally active, multi-targeted tyrosine kinase inhibitor based on a naphthalene ring scaffold. | ||||
| GC81329 | TCB-32 hydrochloride | 169764-95-8 | >97.50% | |
TCB-32 (Compound I-1) hydrochloride is a FGFR1 agonist with an EC 50 of 0.88 μM. | ||||
| GC91419 | CYY292 | 2644673-04-9 | >98.00% | |
CYY292 es un inhibidor de PDGFRα, PDGFRβ, FGFR1, -2 y -3 (IC50s = 5.35, 4.6, 28, 28 y 78 nM respectivamente). | ||||
| GN10527 | Formononetin | 485-72-3 | >99.50% | |
Formononetin es un potente inhibidor de FGFR2 con un IC50 de 4.3μM. La formononetina inhibe de manera eficaz la angiogénesis y el crecimiento tumoral. | ||||
| GN10540 | Fumalic acid | 1135-24-6 | >99.00% | |
A phenol with diverse biological activities.Natural product, extracted from ligusticum chuanxiong. | ||||