GLPBio

Spire2-FMN2 PPI-IN-1 dihydrochloride

Catalog No.: GC79123Purity:>98.50%
COASDSData Sheet
Spire2/FMN2 PPI-IN-1 (Compound 13) dihydrochloride is a selective inhibitory fragment targeting the Spire2-FMN2 interaction, with an IC50 of 62 μM.

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Spire2-FMN2 PPI-IN-1 dihydrochloride
10mM (in 1mL DMSO)In Stock
$101.00
1
5mgIn Stock
$92.00
1
10mgIn Stock
$147.00
1
25mgIn Stock
$295.00
1
50mgIn Stock
$471.00
1
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Description

Spire2/FMN2 PPI-IN-1 (Compound 13) dihydrochloride is a selective inhibitory fragment targeting the Spire2-FMN2 interaction, with an IC50 of 62 μM. Spire2/FMN2 PPI-IN-1 dihydrochloride has affinity for KIND2, with a K d of 87.7 μM, and does not inhibit KIND1. Spire2/FMN2 PPI-IN-1 dihydrochloride can be used for the development of chemical probes for the Spire2-FMN2 interaction [1].

References:
[1]. Radoslaw Kitel, et al. Discovery of Inhibitory Fragments That Selectively Target Spire2-FMN2 Interaction. J Med Chem. 2023 Dec 14;66(23):15715-15727.

Product Documents

Purity:>98.50%Appearance:A solid
COASDSData Sheet

Chemical Properties

Molecular Formula
C11H14Cl2FN3
Molecular Weight
278.15
Solubility
DMSO: 16.67 mg/mL (59.93 mM; ultrasonic and warming and heat to 60°C)
Storage
Store at -20°C
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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