SR10067 |
| Catalog No.GC34810 |
SR10067 is a potent, selective and brain penetrant REV-ERB agonist.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1380548-02-6
Sample solution is provided at 25 µL, 10mM.
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SR10067 is a potent, selective and brain penetrant Rev-Erbα/β agonist, with IC50 values are 160 and 170 nM for Rev-Erbβ and Rev-Erbα, respectively. SR10067 has anxiolytic activity[1][2]. IC50: 160 nM (Rev-Erbβ), 170 nM (Rev-Erbα)[1].
[1]. Banerjee S, et al. Pharmacological targeting of the mammalian clock regulates sleep architecture and emotional behaviour. Nat Commun. 2014 Dec 23;5:5759. doi: 10.1038/ncomms6759. [2]. Thevis M, et al. Emerging drugs affecting skeletal muscle function and mitochondrial biogenesis - Potential implications for sports drug testing programs. Rapid Commun Mass Spectrom. 2016 Mar 15;30(5):635-51.
Average Rating: 5 (Based on Reviews and 9 reference(s) in Google Scholar.)
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