TB-11 is a Cathepsin D inhibitor, with IC50 s of 0.126 nM ( Cathepsin D ), 1.92 nM ( Cathepsin E ), 48.8 nM ( BACE1 ), respectively. TB-11 can be used for tumor research [1].
References:
[1]. Li Z, et al. Design, synthesis, and bioactivities of tasiamide B derivatives as cathepsin D inhibitors. J Pept Sci. 2019 Apr;25(4):e3154.
References:
[1]. Li Z, et al. Design, synthesis, and bioactivities of tasiamide B derivatives as cathepsin D inhibitors. J Pept Sci. 2019 Apr;25(4):e3154.
















