GLPBio

Thalidomide-6-F-5-pip-CHO

Catalog No.: GC80905Purity:>95.00%
Thalidomide-6-F-5-pip-CHO is a synthetic E3 ligase ligand-conjugate that can be used for the synthesis of PROTACs, such as DN1679 [1].

Products are for research use only. Not for human use. We do not sell to patients.


Thalidomide-6-F-5-pip-CHO
Cas No.: 2505502-00-9
10mM (in 1mL DMSO)In Stock
$32.00
1
5mgIn Stock
$29.00
1
10mgIn Stock
$43.00
1
25mgIn Stock
$72.00
1
50mgIn Stock
$115.00
1
100mgIn Stock
$178.00
1

Citations

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    641, 529–536 (2025)
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    618, 1017–1023 (2023)
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    610, 366–372 (2022)
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    Cell
    187(9):2288-2304 (2024)
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    Cell
    183(7):1867-1883 (2020)
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    Science
    388(6745) (2025)
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    387(6734) (2025)
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    Cell Research
    35, 97–116 (2025)
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    34, 683–706 (2024)
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    33, 546–561 (2023)
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    33, 904–922 (2023)
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    31, 1291–1307 (2021)

Description

Thalidomide-6-F-5-pip-CHO is a synthetic E3 ligase ligand-conjugate that can be used for the synthesis of PROTACs, such as DN1679 [1].

References:
[1]. Chen D, et al. Discovery of DN1679 as a Potent, Orally Bioavailable, and Highly Selective CDK12/13 Dual Degrader for the Treatment of Triple-Negative Breast Cancer. J Med Chem. 2026 Jan 22;69(2):1033-1048.

Product Documents

Purity:>95.00%Appearance:A solid

Chemical Properties

CAS No.
2505502-00-9
Molecular Formula
C19H18FN3O5
Molecular Weight
387.36
Solubility
DMSO: 25 mg/mL (64.54 mM; Need ultrasonic)
Storage
Store at -20°C
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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