3′,6-Disinapoylsucrose is a type of oligosaccharide that's effective when taken orally, and it has antidepressant, anti-anxiety, and antioxidant properties. 3′,6-Disinapoylsucrose inhibits neuronal apoptosis by lowering the ratio of Bax to Bcl-2 in hippocampal neurons, and it enhances cognitive function in APP/PS1 transgenic mice by activating the CREB/BDNF signaling pathway [1] [2].
References:
[1]. Jiaqi Yuan, et al. 3,6'-Disinapoyl sucrose alleviates cognitive deficits in APP/PS1 transgenic mice. J Neurophysiol. 2023 Nov 1;130(5):1174-1182.
[2]. Jie Zhang, et al. Anxiolytic effects, metabolism and plasma pharmacokinetics of 3, 6' -disinapoylsucrose. Biomed Pharmacother. 2022 May:149:112913.
References:
[1]. Jiaqi Yuan, et al. 3,6'-Disinapoyl sucrose alleviates cognitive deficits in APP/PS1 transgenic mice. J Neurophysiol. 2023 Nov 1;130(5):1174-1182.
[2]. Jie Zhang, et al. Anxiolytic effects, metabolism and plasma pharmacokinetics of 3, 6' -disinapoylsucrose. Biomed Pharmacother. 2022 May:149:112913.