4-Thiouracil (Synonyms: 2-hydroxy-4-Mercaptopyrimidine, NSC 43288, 4-Thiopyrimidin-2-one, 4-TU) |
| Catalog No.GC40477 |
4-Thiouracil is a site-specific, photoactivatable probe used to detect RNA structures and nucleic acid-nucleic acid contacts.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 591-28-6
Sample solution is provided at 25 µL, 10mM.
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4-Thiouracil is a site-specific, photoactivatable probe used to detect RNA structures and nucleic acid-nucleic acid contacts. It absorbs ultraviolet light >300 nm and, in the presence of oxygen, acts as an energy donor to produce singlet oxygen by triplet-triplet energy transfer. The highly reactive oxygen species then reacts readily with 4-thiouracil, leading to the production of uracil and uracil-6-sulfonate, which is fluorescent at a wavelength of ~390 nm. 4-Thiouracil is used as a T. gondii uracil phosphoribosyltransferase substrate to produce 4-thiouridine monophosphate, which can ultimately be incorporated into RNA.
Average Rating: 5 (Based on Reviews and 15 reference(s) in Google Scholar.)
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