Ac-DEVD-pNA is a colorimetric substrate for caspase-3 (CPP32) and related cysteine proteases.
References:
[1]. Talanian RV, et al. Substrate specificities of caspase family proteases. J Biol Chem. 1997 Apr 11;272(15):9677-82.
Ac-DEVD-pNA
Catalog No.: GC12734Purity:>98.50%Synonyms: Ac-Asp-Glu-Val-Asp-pNA
Ac-DEVD-pNA is a colorimetric substrate for caspase-3 (CPP32) and related cysteine proteases.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 189950-66-1
1mgIn Stock
$32.00
1
5mgIn Stock
$86.00
1
10mgIn Stock
$122.00
1
| Pack Size | Price | Availability | Quantity | Action |
|---|---|---|---|---|
| 1mg | $32.00 | In Stock | 1 | |
| 5mg | $86.00 | In Stock | 1 | |
| 10mg | $122.00 | In Stock | 1 |
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Cell187(9):2288-2304 (2024)
Cell183(7):1867-1883 (2020)
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Science387(6734) (2025)
Cell Research35, 97–116 (2025)
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Description
Product Documents
Purity:>98.50%Appearance:A solid
Chemical Properties
CAS No.
189950-66-1
Synonyms
Ac-Asp-Glu-Val-Asp-pNA
Chemical Name
7-(2-carboxyethyl)-4-(carboxymethyl)-10-isopropyl-13-((4-nitrophenyl)carbamoyl)-2,5,8,11-tetraoxo-3,6,9,12-tetraazapentadecan-15-oic acid
SMILES
O=C(O)CCC(NC(C(NC(C)=O)CC(O)=O)=O)C(NC(C(C)C)C(NC(CC(O)=O)C(NC1=CC=C([N+]([O-])=O)C=C1)=O)=O)=O
Molecular Formula
C26H34N6O13
Molecular Weight
638.58
Solubility
≥ 6.39mg/mL in Water
Storage
Store at -20°C
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.
CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility
g/mol
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