Antiparasitics

Amiprofos-methyl (APM) is a phosphoric amide herbicide.

Cellocidin is an antibiotic originally isolated from S.

Cathepsin L Inhibitor (Z-FY-CHO) is a compound that can specifically inhibit the activity of Cathepsin L (Ki = 0.185nM) and is used to study the role of Cathepsin L in lysosomal function and protein degradation within cells.

Psoromic acid is an inhibitor of Rab geranylgeranyl transferase (IC50 = 1.3 uM) and P.

1-Palmitoyl-2-hydroxy-sn-glycero-3-PE is a naturally-occurring lysophospholipid.

(±)-Dunnione is a naturally occurring naphthoquinone with diverse biological activities.

Tetromycin B is a cysteine protease inhibitor with Ki values of 0.62, 1.42, 32.5, and 1.59 μM for rhodesain, falcipain-2, cathepsin L, and cathepsin B, respectively.

Nimbolide is a triterpene derived from the leaves and flowers of Azadirachta indica L. Nimbolide inhibits NF- κ B induces tumor cell apoptosis. Nimbolide inhibited CDK4 / Cdk6 kinase activity. Nimbolide inhibits NF- κ B. Wnt, PI3K Akt, MAPK and JAK-STAT signaling pathways.

Puromycin dihydrochloride is the dihydrochloride salt of puromycin. Puromycin is an aminoglycoside antibiotic that inhibits protein synthesis.

Roridin E is a macrocyclic trichothecene mycotoxin that has been found in M.

Drimentine B is a terpenylated diketopiperazine antibiotic originally isolated from Actinomycete bacteria.

(-)-Epigallocatechin gallate-d3/d4 is intended for use as an internal standard for the quantification of (-)-epigallocatechin gallate by GC- or LC-MS.

D-Eritadenine is an adenosine analog and a potent, reversible inhibitor of S-adenosylhomocysteine hydrolase (SAAH; IC50 = 7 nM).

Pyrocoll is a bacterial metabolite originally isolated from Streptomyces.

2-epi-Abamectin is a degradation product of abamectin.

δ2-Avermectin B1a is a degradation product formed by the reversible base-catalyzed isomerization of ivermectin B1a.

During unfavorable environmental conditions, C.

Brevicompanine B is a fungal metabolite originally isolated from P.

Eprinomectin B1a is a major component (>90%) of the antiparasitic compound eprinomectin, which also contains eprinomectin B1b and belongs to the avermectin family of insecticides and anthelmintics.

Steffimycin B is an anthracycline bacterial metabolite originally isolated from Streptomyces.

2,3-Dehydro-3,4-dihydro ivermectin is an analog of ivermectin and an anthelmintic.

epi-Ivermectin B1a is a degradation product formed by the reversible base-catalyzed isomerization of ivermectin B1a.