Cellocidin (Synonyms: Acetylenedicarboxylic Acid, NSC 38643, NSC 65381) |
| Catalog No.GC18392 |
Cellocidin is an antibiotic originally isolated from S.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 543-21-5
Sample solution is provided at 25 µL, 10mM.
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Cellocidin is an antibiotic originally isolated from S. chibaensis. It is active against various bacterial strains including M. tuberculosis and against the trypanosomes T. brucei and T. rhodesiense (IC50s = 150 and 30 ng/ml, respectively). It inhibits proliferation of LCL1 and LCL2 cells transformed by Epstein-Barr virus (EBV), activates the c-Myc and NF-κB pathways in BC3 and LCL1 cells, and induces necrotic cell death in B cells infected with gammaherpes virus. Cellocidin (100-200 ppm) is protective against bacterial leaf blight in rice plants and inhibits α-ketoglutarate oxidation in X. oryzae, the bacterium that causes leaf blight, when used at a concentration of 1 ppm, suggesting that it inhibits the citric acid cycle. Formulations containing cellocidin have been used as agricultural pesticides.
Review for Cellocidin
Average Rating: 5 (Based on Reviews and 11 reference(s) in Google Scholar.)
Review for Cellocidin
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