PD-1/PD-L1 inhibitor 2 (Synonyms: BMS202) |
رقم الكتالوجGC16762 |
مثبط PD-1 / PD-L1 2 هو مثبط قوي وغير معقد PD-1 / PD-L1 مع IC50 من 18 نانومتر و KD 8 μ ؛ M. يربط مثبط PD-1 / PD-L1 2 بـ PD-L1 ويمنع تفاعل PD-1 / PD-L1 البشري. مثبط PD-1 / PD-L1 2 له نشاط مضاد للأورام.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1675203-84-5
Sample solution is provided at 25 µL, 10mM.
BMS-202 is a potent PD-1/PD-L1 inhibitor, which binds to PD-1 and inhibits human PD-1/PD-L1 interaction, with an IC50 of 18 nM[1].
References:
[1]. Zak KM, et al. Structural basis for small molecule targeting of the programmed death ligand 1 (PD-L1). Oncotarget. 2016 May 24;7(21):30323-35.
Average Rating: 5
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