DM4-SMCC |
رقم الكتالوجGC38479 |
DM4-SMCC عبارة عن اتحاد رابط دوائي لـ ADC مع نشاط مضاد للورم باستخدام DM4 (عامل مضاد للأوبولين) ، مرتبط عبر رابط SMCC غير القابل للانقسام
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Cas No.: 1228105-52-9
Sample solution is provided at 25 µL, 10mM.
DM4-SMCC is a drug-linker conjugate for ADC with antitumor activity by using DM4 (an antitubulin agent), linked via the non-cleavable SMCC linker[1].
[1]. Singh R, et al. A New Triglycyl Peptide Linker for Antibody-Drug Conjugates (ADCs) with Improved TargetedKilling of Cancer Cells. Mol Cancer Ther. 2016 Jun;15(6):1311-20.
Average Rating: 5
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