Recently Updated Products

Recently Updated Products list

• GC16450Prednisone

  Glucocorticoid receptor agonist

• GC74216AF488 DBCO ditriethylamine

  AF488 DBCO ditrietlamine is the ditrietlamine salt form of AF488 DBCO.

• GC111391-Stearoyl-2-Arachidonoyl-sn-glycero-3-PC

  A phospholipid

• GC59006Azide-PEG4-Amine

  Oligoethylene glycols are versatile hydrophilic linkers. Each monomer has a length of 3.43 Å, so that the length of PEG4 is around 14 Å (1.4 nm). Azide-PEG4-Amine is a bifunctional compound with an amine group that can be modified by acylation by activated esters or similar carbonyl compounds, and an azide group that is suitable for Click chemistry reactions. PEG4 is highly hydrophilic and biocompatible.

• GC49003(E)-Ajoene

  A disulfide with diverse biological activities

• GC4652722-NBD Cholesterol

  A fluorescent cholesterol analog

• GC45937trans-β-Ocimene

  A monoterpene

• GC12153Zebularine

  Zebularine, a cytidine lacking the 4-amino group, is a DNMT inhibitor that inhibits DNA methylation.

• GC14683Sunitinib malate

  A multi-kinase inhibitor

• GF03018T4 DNA Ligase(with 10X Ligation Buffer)

  -

• GC26270Bovine Serum Albumin(Fatty Acid & lgG Free)

  Bovine Serum Albumin(Fatty Acid & lgG Free) is a globular protein and oligonucleotide-binding protein composed of 583 amino acid residues and consisting of three identical α-helical domains.

• GC13118Dihydro-β-erythroidine hydrobromide

  Dihydro-β-erythroidine (DHβE) hydrobromide is a potent, orally active, and competitive antagonist of neuronal nAChRs.

• GC70439PF-739

  PF-739 is an AMPK activator. PF-739 reduces plasma glucose levels by activating all 12 heterotrimeric AMPK complexes.

• GC65429Capillarisin

  Capillarisin, as a constituent from Artemisiae Capillaris herba, is found to exert anti-inflammatory and antioxidant properties.

• GC19973Poly-D-lysine hydrobromide (M.W 70000~150000)

  Poly-D-lysine hydrobromide (MW 70,000 ~ 150,000) is a cell non-specific attachment factor that is often used to promote the adhesion of cells to solid matrices.

• GC26535NRG1-beta 1 Protein, Human

  NRG-1 protein, belonging to the structurally related peptide growth factor family of Human, originates from alternative splicing genes and induces Fn14 expression in MCF7 cells.

• GC79400SIYNFEKL acetate

  -

• GC49480Salicylic Acid-d4

  Salicylic Acid-d4 is the deuterium labeled 2-Carboxyphenol.

• GC65915TLR7/8 agonist 4

  TLR7/8 agonist 4 (compound 41) is a potent TLR7/8 agonist. TLR7/8 agonist 4 has anti-cancer activity.

• GC78914TTP-6171

  TTP-6171 is a non-covalent inhibitor of Monkeypox virus I7L protease, and it can be used for research on poxvirus infections [1] .

• GC19526Cyclic di-GMP disodium

  Cyclic di-GMP disodium is a cyclic dinucleotide signaling molecule synthesized by bacteria and is a STING agonist.

• GB60339Palladium (II) acetate

  -

• GC69329KDM5-C49 hydrochloride

  KDM5-C49 (KDOAM-20) hydrochloride is an effective and selective inhibitor of KDM5 demethylases, with IC50 values of 40 nM, 160 nM, and 100 nM for KDM5A, KDM5B, and KDM5C respectively. It can be used in cancer research.

• GC43305Compound 48/80 (hydrochloride)

  Compound 48/80 trihydrochloride is a mixture of condensation products of N-methyl-p-methoxyphenethylamine with formaldehyde.

• GC11908Cisplatin

  Cisplatin, a platinum-containing anticancer drug, is one of the most commonly used cytotoxic agents for the treatment of a variety of solid malignant tumors.

• GC41390Aldosterone

  Aldosterone is a steroid hormone secreted by the adrenal cortex and is the principle mineralocorticoid controlling sodium and potassium balance

• GC39080Spathulenol

  Spathulenol is isolated from Psidium guineense Sw, and has antioxidant, anti-inflammatory, antiproliferative and antimycobacterial activities. Spathulenol shows a high antioxidant activity with an IC50 of 85.60 μg/mL in the DPPH system.

• GB60317Oleyl oleate

  -

• GC18147Tretinoin (Aberela)

  Tretinoin (Aberela)is a vitamin A-derived, non-peptidic, small lipophilic molecule that acts as a ligand for nuclear RA receptors (RARs), with a K d value of 17nM for PPARβ/δ.

• GC15307SU5416

  SU5416 is a small-molecule Flk-1/KDR inhibitor that inhibits autophosphorylation of the Flk-1 receptor, with an IC 50 value of 1.23μM.

• GC39451Testosterone (propionate)

  Testosterone propionate is a slower releasing anabolic steroid used mainly in the treatment of low testosterone levels in men.

• GC26716Polyvinylpyrrolidone (PVP) (M.W.~360000)

  Used in molecular biology, nucleic acid hybridization tested, mol wt 360,000

• GC68230MitoSOX Red

  MitoSOX Red is a live cell fluorescent probe targeting mitochondria with maximum excitation/emission light of 510/580 nm.

• GC30535Transdermal Peptide (TD 1 (peptide))

  Transdermal Peptide (TD 1 (peptide)) is a peptide chaperon with high permeability that facilitates several proteins' transdermal delivery via topical co-administration.

• GC49790Reuterin

  Reuterin is a broad-spectrum antimicrobial small molecule produced by Lactobacillus reuteri during anaerobic fermentation of glycerol.

• GC16879Tubercidin

  Tubercidin is an adenosine analog with potent antimycobacterial and antitumor bioactivities.

• GN10388Gallic acid

  Gallic acid is a 3,4,5-trihydroxybenzoic acid phenolic compound with antioxidant, anti-inflammatory and antitumor activities.

• GK10040One-step TUNEL Apoptosis Detection Kit (Green, FITC)

  One-step TUNEL Apoptosis Detection Kit (Green, FITC) provides a fast and highly efficient method for detecting the degree of nuclear DNA fragmentation in cells and tissues during apoptosis, Ex/Em = 492/517nm.

• GK10041One-step TUNEL Apoptosis Detection Kit (Orange, CY3)

  One-step TUNEL Apoptosis Detection Kit (Orange, CY3) provides a fast and highly efficient method for detecting the degree of nuclear DNA fragmentation in cells and tissues during apoptosis, Ex/Em = 550/570nm.

• GC30950TTA-Q6

  TTA-Q6 is a selective antagonist of T-type Ca2+ channel and can be used in neurological research.

• GC10893Dutasteride

  5-alpha-reductase inhibitor

• GP10065Endomorphin-1

  -

• GC19377Visomitin (SKQ1)

  Visomitin is a new antioxidant with the highest mitochondrion membrane penetrating ability and potent antioxidant capability.

• GC12512Losartan Carboxylic Acid

  Losartan Carboxylic Acid is a human active metabolite of the angiotensin II receptor type 1 (AT1) receptor antagonist losartan, with an IC 50 of 139.3μM for inhibiting cAMP PDE (phosphodiesterase) activity.

• GC11008Necrostatin-1

  Necrostatin-1 is a novel small molecule inhibitor of necroptosis. Necrostatin-1 inhibits RIP1 kinase activity (EC 50 =182nM) through allosteric binding.

• GC10854IDE 2

  IDE 2 is a definitive endoderm inducer with small molecule activity and activates the TGF-β/Nodal signaling pathway.

• GC61473Trastuzumab deruxtecan

  Trastuzumab deruxtecan is a human epidermal growth factor receptor 2 (HER2)-targeted antibody-drug conjugate (ADC) composed of a humanized anti-human HER2 (anti-hHER2) antibody, an enzymatically cleavable peptide linker, and a topoisomerase I inhibitor (DX-8951 derivative).

• GB57802Cobalt(II)nitratehexa hydrate

  Cobalt(II)nitratehexa hydrateis a cobalt ion source and common starting material used for synthesizing various cobalt-containing compounds.

• GF15503Carpinontriol B

  -

• GC50492OB-1

  OB-1 is a potent stomatin-like protein-3 (STOML3) inhibitor that inhibits Piezo1 currents with an IC 50 value of 10nM.

• GC11074BIBP 3226 trifluoroacetate

  BIBP 3226 trifluoroacetate is a potent non-peptide neuropeptide Y (NPY) Y1 receptor antagonist with K i values of 1.1, 79, and 108nM for rNPY Y1, hNPFF2, and rNPFF, respectively.

• GC12793RITA (NSC 652287)

  RITA (NSC 652287) is a tricyclic thiophene derivative that binds to p53dN (K d =1.5nM) and blocks the p53-HDM-2 interaction, thereby inhibiting p53 ubiquitination.

• GK10027Bradford Protein Quantification Kit

  The Bradford Protein Quantification Kit is a kit for rapid determination of protein concentrations in the range of 0.025-2mg/ml.

• GC69899SIRT6 activator 12q

  SIRT6 activator 12q is a selective SIRT6 activator (IC₅₀ = 0.58μM).

• GC44085L-Sulforaphene

  L-Sulforaphene is a natural isothiocyanate with anti-inflammatory, anticancer, and antioxidant effects.

• GC70717Benitrobenrazide (Hexokinase 2 inhibitor 1)

  Benitrobenrazide (Hexokinase 2 inhibitor 1) inhibits glycolysis by directly targeting HK2.

• GC43367D-(+)-Glucose-13C6

  D-(+)-Glucose-13C6 is the stable isotope labeled counterpart of D-(+)-Glucose and is mainly used as an internal standard for the quantification of D-(+)-Glucose by GC- or LC-MS measurement.

• GC69706PI3K/AKT-IN-1

  PI3K/AKT-IN-1 is a potent PI3K/AKT dual inhibitor with IC 50 values of 6.99μM, 4.01μM, and 3.36μM for PI3Kγ, PI3Kδ and AKT, respectively.

• GC33044RMC-4550

  RMC-4550 is an orally active allosteric inhibitor of SHP2 (IC₅₀=0.583nM).

• GA22584Hippuryl-Arg-OH

  Hippuryl-Arg-OH is a fluorescent signal substrate used in enzyme activity assays for the identification and cleavage of peptide bonds containing arginine.

• GC16591d[Cha4]-AVP

  d[Cha4]-AVPis a potent and selective Vasopressin (AVP) V1b receptor agonist with a K i value of 1.2nM, 151nM for V1b and V1a receptors, respectively.

• GC40758Gly-Phe-β-naphthylamide

  Gly-Phe-β-naphthylamide is a cathepsin C substrate and lysosomal perturbing agent.

• GC18157Thymoquinone

  Thymoquinone is an orally active natural product isolated from Nigella glandulifera .

• GB57006Ammonium iron(II) sulfate hexahydrate

  -

• GC32921LOM612

  LOM612 is a potent FOXO relocator, with an EC50 value of 1.5 μM in U2fox RELOC cells.

• GC80849AtPep1 TFA

  AtPep1 TFA is an endogenous inducer of innate immune responses.

• GC71375GPR61 Inverse agonist 1

  GPR61 Inverse agonist 1 (Compound 1) is a GPR61 inverse agonist (IC50: 11 nM).

• GC27810Convolamine

  Convolamine is an alkaloid found in Convolvulus pluricaulis and an effective positive modulator of the sigma-1 receptor (IC 50 = 289 nM), exhibiting cognitive and neuroprotective properties.

• GC31636Cholesteryl linoleate

  A cholesterol ester

• GB60393Perfluorooctanesulfonamide

  -

• GC81902SR10098

  SR10098 is a benzimidazole-based Nurr1 activator with an EC 50 of 24 nM against full-length Nurr1.

• GC81906N-Phenyl-1H-benzimidazol-6-amine

  -

• GC819045MPEP

  -

• GC81903Zaloganan acetate

  -

• GN10700Plantamajoside

  Plantamajoside is a phenylpropanoid glycoside compound with NF-κB and MAPK signaling pathway inhibition and antioxidant activity.

• GC11108Abiraterone acetate

  A CYP17A1 inhibitor

• GC81901M918 acetate

  -

• GC81905α-Methyl-L-tryptophan

  -

• GC39005Nordalbergin

  Nordalbergin, a coumarin isolated from the wood bark of Dalbergia sissoo. Nordalbergin shows strong activity in the induction of differentiation of HL-60.

• GC37999β-Anhydroicaritin

  β-Anhydroicaritin is isolated from Boswellia carterii Birdware, has important biological and pharmacological effects, such as antiosteoporosis, estrogen regulation and antitumor properties.

• GC39731Warfarin sodium

  Warfarin sodium is an orally active vitamin K antagonist.

• GC19992Clodronate Liposomes

  Macrophage scavenger - Clodronate Liposomes Clodronate Liposomes were developed by Professor Nico van Rooijen of Vrije University in Amsterdam, Netherlands, introduces membrane-impermeable clodronate into the cell through the entosis mechanism of macrophages. Under the action of macrophage lysosomal phosphatase, clodronate dissolved in the aqueous phase of liposomes is released and accumulated in the cells. When it reaches a certain concentration, it can induce macrophages to enter the apoptosis process, and then the macrophages were eliminated. Clodronate Liposomes are suitable for various injection methods, such as intravenous injection, intraperitoneal injection, subcutaneous injection, intranasal injection and testicular injection, etc. The injection volume is related to the body weight of the mice, the injection period, the injection method and the purpose of the experiment. Solution 10 mM Na 2 HPO 4 , 10 mM NaH 2 PO 4 , 140 mM NaCl Concentration 5 mg/mL Lipid composition Phosphatidylcholine and cholesterol Structure

• GC27581Control Liposomes(PBS)

  Disodium clodronate is a specific macrophage-killing agent that can eliminate macrophages in tissues by inducing macrophage apoptosis.

• GC494437α-hydroxy Cholesterol

  7α-hydroxy Cholesterol is an endogenous oxidized cholesterol metabolite.

• GC31360Taspoglutide (ITM077)

  Taspoglutide (ITM077) is a novel analog of human glucagon-like peptide-1 [hGLP-1(7-36)NH 2 ] in clinical development for the treatment of type 2 diabetes. Taspoglutide inhibits VEGFR2 in CHO cells with an IC 50 value of 4.6±0.6nM.

• GC70621NBD-Pen

  NBD-Pen is a high-sensitivity, specific fluorescence probefor lipid radicals (λex: 478 nm, λem: 534 nm).

• GC15161Calcium D-Panthotenate

  Calcium D-Panthotenate (Vitamin B5 calcium salt), a vitamin, can reduce the patulin content of the apple juice.

• GC14927Trazodone HCl

  Trazodone (hydrochloride) (AF-1161) is an antidepressant belonging to the class of serotonin receptor antagonists and reuptake inhibitors for treatment of anxiety disorders.

• GC26002Trazodone

  Trazodone is a 5-hydroxytryptamine antagonist and reuptake inhibitor (SARI).

• GC30112PAT-1251

  PAT-1251 is a lysyl oxidase-like 2 (LOXL2; IC 50 =0.71μM) inhibitor.

• GC4078111(Z),14(Z),17(Z)-Eicosatrienoic Acid

  11(Z),14(Z),17(Z)-Eicosatrienoic Acid is an ω-3 long-chain polyunsaturated fatty acid and an endogenous metabolite, can serve as a metabolic intermediate in the conversion of α-linolenic acid to long-chain ω-3 fatty acids such as EPA and DHA.

• GC13645nor-Binaltorphimine dihydrochloride

  nor-Binaltorphimine dihydrochloride is a potent and selective κ opioid receptor (KOR) antagonist.

• GC63604Sparfosic acid

  Sparfosic acid, a DNA antimetabolite agent, is a potent inhibitor of aspartate transcarbamoyl transferase, the enzyme catalyzing the second step of de novo pyrimidine biosynthesis.

• GC33094GC7 Sulfate

  GC7 Sulfate is the sulfate salt of N1-guanyl-1,7-diaminoheptane and a deoxyhypusine synthase (DHPS) inhibitor.

• GC30183Acridine Orange 10-Nonyl Bromide (Nonylacridine orange)

  Acridine Orange 10-Nonyl Bromide (Nonylacridine orange) is a mitochondria-targeting fluorescent probe (excitation wavelength: 489nm; emission wavelength: 525nm).

• GC62372Cyclic-di-GMP sodium

  Cyclic-di-GMP sodium is a STING agonist and a bacterial second messenger that coordinates different aspects of bacterial growth and behavior, including motility, virulence, biofilm formation, and cell cycle progression. Cyclic-di-GMP sodium has anti-cancer cell proliferation activity and also induces elevated CD4 receptor expression and cell cycle arrest. Cyclic-di-GMP sodium can be used in cancer research.

• GC60186HBC620

  HBC620 is an HBC-like fluorophore, a GFP fluorophore-like synthetic dye, with a maximum excitation wavelength of 577nm and a maximum emission wavelength of 620nm.

• GC502444-ethynyl-N-ethyl-1,8-naphthalimide

  Click-activated fluorescent probe

• GN10341Acetate gossypol

  Acetate gossypol is a lipid-soluble polyphenolic compound extracted from the cotton plant with antifertility, antioxidant, and anticancer properties.

• GN10082Gossypol

  Gossypol is a lipid-soluble polyphenolic compound extracted from the cotton plant with antifertility, antioxidant, and anticancer properties.

• GC16450
  Prednisone

  Glucocorticoid receptor agonist

• GC74216
  AF488 DBCO ditriethylamine

  AF488 DBCO ditrietlamine is the ditrietlamine salt form of AF488 DBCO.

• GC11139
  1-Stearoyl-2-Arachidonoyl-sn-glycero-3-PC

  A phospholipid

• GC59006
  Azide-PEG4-Amine

  Oligoethylene glycols are versatile hydrophilic linkers. Each monomer has a length of 3.43 Å, so that the length of PEG4 is around 14 Å (1.4 nm). Azide-PEG4-Amine is a bifunctional compound with an amine group that can be modified by acylation by activated esters or similar carbonyl compounds, and an azide group that is suitable for Click chemistry reactions. PEG4 is highly hydrophilic and biocompatible.

• GC49003
  (E)-Ajoene

  A disulfide with diverse biological activities

• GC46527
  22-NBD Cholesterol

  A fluorescent cholesterol analog

• GC45937
  trans-β-Ocimene

  A monoterpene

• GC12153
  Zebularine

  Zebularine, a cytidine lacking the 4-amino group, is a DNMT inhibitor that inhibits DNA methylation.

• GC14683
  Sunitinib malate

  A multi-kinase inhibitor

• GF03018
  T4 DNA Ligase(with 10X Ligation Buffer)

  -

• GC26270
  Bovine Serum Albumin(Fatty Acid & lgG Free)

  Bovine Serum Albumin(Fatty Acid & lgG Free) is a globular protein and oligonucleotide-binding protein composed of 583 amino acid residues and consisting of three identical α-helical domains.

• GC13118
  Dihydro-β-erythroidine hydrobromide

  Dihydro-β-erythroidine (DHβE) hydrobromide is a potent, orally active, and competitive antagonist of neuronal nAChRs.

• GC70439
  PF-739

  PF-739 is an AMPK activator. PF-739 reduces plasma glucose levels by activating all 12 heterotrimeric AMPK complexes.

• GC65429
  Capillarisin

  Capillarisin, as a constituent from Artemisiae Capillaris herba, is found to exert anti-inflammatory and antioxidant properties.

• GC19973
  Poly-D-lysine hydrobromide (M.W 70000~150000)

  Poly-D-lysine hydrobromide (MW 70,000 ~ 150,000) is a cell non-specific attachment factor that is often used to promote the adhesion of cells to solid matrices.

• GC26535
  NRG1-beta 1 Protein, Human

  NRG-1 protein, belonging to the structurally related peptide growth factor family of Human, originates from alternative splicing genes and induces Fn14 expression in MCF7 cells.

• GC79400
  SIYNFEKL acetate

  -

• GC49480
  Salicylic Acid-d4

  Salicylic Acid-d4 is the deuterium labeled 2-Carboxyphenol.

• GC65915
  TLR7/8 agonist 4

  TLR7/8 agonist 4 (compound 41) is a potent TLR7/8 agonist. TLR7/8 agonist 4 has anti-cancer activity.

• GC78914
  TTP-6171

  TTP-6171 is a non-covalent inhibitor of Monkeypox virus I7L protease, and it can be used for research on poxvirus infections [1] .

• GC19526
  Cyclic di-GMP disodium

  Cyclic di-GMP disodium is a cyclic dinucleotide signaling molecule synthesized by bacteria and is a STING agonist.

• GB60339
  Palladium (II) acetate

  -

• GC69329
  KDM5-C49 hydrochloride

  KDM5-C49 (KDOAM-20) hydrochloride is an effective and selective inhibitor of KDM5 demethylases, with IC50 values of 40 nM, 160 nM, and 100 nM for KDM5A, KDM5B, and KDM5C respectively. It can be used in cancer research.

• GC43305
  Compound 48/80 (hydrochloride)

  Compound 48/80 trihydrochloride is a mixture of condensation products of N-methyl-p-methoxyphenethylamine with formaldehyde.

• GC11908
  Cisplatin

  Cisplatin, a platinum-containing anticancer drug, is one of the most commonly used cytotoxic agents for the treatment of a variety of solid malignant tumors.

• GC41390
  Aldosterone

  Aldosterone is a steroid hormone secreted by the adrenal cortex and is the principle mineralocorticoid controlling sodium and potassium balance

• GC39080
  Spathulenol

  Spathulenol is isolated from Psidium guineense Sw, and has antioxidant, anti-inflammatory, antiproliferative and antimycobacterial activities. Spathulenol shows a high antioxidant activity with an IC50 of 85.60 μg/mL in the DPPH system.

• GB60317
  Oleyl oleate

  -

• GC18147
  Tretinoin (Aberela)

  Tretinoin (Aberela)is a vitamin A-derived, non-peptidic, small lipophilic molecule that acts as a ligand for nuclear RA receptors (RARs), with a K d value of 17nM for PPARβ/δ.

• GC15307
  SU5416

  SU5416 is a small-molecule Flk-1/KDR inhibitor that inhibits autophosphorylation of the Flk-1 receptor, with an IC 50 value of 1.23μM.

• GC39451
  Testosterone (propionate)

  Testosterone propionate is a slower releasing anabolic steroid used mainly in the treatment of low testosterone levels in men.

• GC26716
  Polyvinylpyrrolidone (PVP) (M.W.~360000)

  Used in molecular biology, nucleic acid hybridization tested, mol wt 360,000

• GC68230
  MitoSOX Red

  MitoSOX Red is a live cell fluorescent probe targeting mitochondria with maximum excitation/emission light of 510/580 nm.

• GC30535
  Transdermal Peptide (TD 1 (peptide))

  Transdermal Peptide (TD 1 (peptide)) is a peptide chaperon with high permeability that facilitates several proteins' transdermal delivery via topical co-administration.

• GC49790
  Reuterin

  Reuterin is a broad-spectrum antimicrobial small molecule produced by Lactobacillus reuteri during anaerobic fermentation of glycerol.

• GC16879
  Tubercidin

  Tubercidin is an adenosine analog with potent antimycobacterial and antitumor bioactivities.

• GN10388
  Gallic acid

  Gallic acid is a 3,4,5-trihydroxybenzoic acid phenolic compound with antioxidant, anti-inflammatory and antitumor activities.

• GK10040
  One-step TUNEL Apoptosis Detection Kit (Green, FITC)

  One-step TUNEL Apoptosis Detection Kit (Green, FITC) provides a fast and highly efficient method for detecting the degree of nuclear DNA fragmentation in cells and tissues during apoptosis, Ex/Em = 492/517nm.

• GK10041
  One-step TUNEL Apoptosis Detection Kit (Orange, CY3)

  One-step TUNEL Apoptosis Detection Kit (Orange, CY3) provides a fast and highly efficient method for detecting the degree of nuclear DNA fragmentation in cells and tissues during apoptosis, Ex/Em = 550/570nm.

• GC30950
  TTA-Q6

  TTA-Q6 is a selective antagonist of T-type Ca2+ channel and can be used in neurological research.

• GC10893
  Dutasteride

  5-alpha-reductase inhibitor

• GP10065
  Endomorphin-1

  -

• GC19377
  Visomitin (SKQ1)

  Visomitin is a new antioxidant with the highest mitochondrion membrane penetrating ability and potent antioxidant capability.

• GC12512
  Losartan Carboxylic Acid

  Losartan Carboxylic Acid is a human active metabolite of the angiotensin II receptor type 1 (AT1) receptor antagonist losartan, with an IC 50 of 139.3μM for inhibiting cAMP PDE (phosphodiesterase) activity.

• GC11008
  Necrostatin-1

  Necrostatin-1 is a novel small molecule inhibitor of necroptosis. Necrostatin-1 inhibits RIP1 kinase activity (EC 50 =182nM) through allosteric binding.

• GC10854
  IDE 2

  IDE 2 is a definitive endoderm inducer with small molecule activity and activates the TGF-β/Nodal signaling pathway.

• GC61473
  Trastuzumab deruxtecan

  Trastuzumab deruxtecan is a human epidermal growth factor receptor 2 (HER2)-targeted antibody-drug conjugate (ADC) composed of a humanized anti-human HER2 (anti-hHER2) antibody, an enzymatically cleavable peptide linker, and a topoisomerase I inhibitor (DX-8951 derivative).

• GB57802
  Cobalt(II)nitratehexa hydrate

  Cobalt(II)nitratehexa hydrateis a cobalt ion source and common starting material used for synthesizing various cobalt-containing compounds.

• GF15503
  Carpinontriol B

  -

• GC50492
  OB-1

  OB-1 is a potent stomatin-like protein-3 (STOML3) inhibitor that inhibits Piezo1 currents with an IC 50 value of 10nM.

• GC11074
  BIBP 3226 trifluoroacetate

  BIBP 3226 trifluoroacetate is a potent non-peptide neuropeptide Y (NPY) Y1 receptor antagonist with K i values of 1.1, 79, and 108nM for rNPY Y1, hNPFF2, and rNPFF, respectively.

• GC12793
  RITA (NSC 652287)

  RITA (NSC 652287) is a tricyclic thiophene derivative that binds to p53dN (K d =1.5nM) and blocks the p53-HDM-2 interaction, thereby inhibiting p53 ubiquitination.

• GK10027
  Bradford Protein Quantification Kit

  The Bradford Protein Quantification Kit is a kit for rapid determination of protein concentrations in the range of 0.025-2mg/ml.

• GC69899
  SIRT6 activator 12q

  SIRT6 activator 12q is a selective SIRT6 activator (IC₅₀ = 0.58μM).

• GC44085
  L-Sulforaphene

  L-Sulforaphene is a natural isothiocyanate with anti-inflammatory, anticancer, and antioxidant effects.

• GC70717
  Benitrobenrazide (Hexokinase 2 inhibitor 1)

  Benitrobenrazide (Hexokinase 2 inhibitor 1) inhibits glycolysis by directly targeting HK2.

• GC43367
  D-(+)-Glucose-13C6

  D-(+)-Glucose-13C6 is the stable isotope labeled counterpart of D-(+)-Glucose and is mainly used as an internal standard for the quantification of D-(+)-Glucose by GC- or LC-MS measurement.

• GC69706
  PI3K/AKT-IN-1

  PI3K/AKT-IN-1 is a potent PI3K/AKT dual inhibitor with IC 50 values of 6.99μM, 4.01μM, and 3.36μM for PI3Kγ, PI3Kδ and AKT, respectively.

• GC33044
  RMC-4550

  RMC-4550 is an orally active allosteric inhibitor of SHP2 (IC₅₀=0.583nM).

• GA22584
  Hippuryl-Arg-OH

  Hippuryl-Arg-OH is a fluorescent signal substrate used in enzyme activity assays for the identification and cleavage of peptide bonds containing arginine.

• GC16591
  d[Cha4]-AVP

  d[Cha4]-AVPis a potent and selective Vasopressin (AVP) V1b receptor agonist with a K i value of 1.2nM, 151nM for V1b and V1a receptors, respectively.

• GC40758
  Gly-Phe-β-naphthylamide

  Gly-Phe-β-naphthylamide is a cathepsin C substrate and lysosomal perturbing agent.

• GC18157
  Thymoquinone

  Thymoquinone is an orally active natural product isolated from Nigella glandulifera .

• GB57006
  Ammonium iron(II) sulfate hexahydrate

  -

• GC32921
  LOM612

  LOM612 is a potent FOXO relocator, with an EC50 value of 1.5 μM in U2fox RELOC cells.

• GC80849
  AtPep1 TFA

  AtPep1 TFA is an endogenous inducer of innate immune responses.

• GC71375
  GPR61 Inverse agonist 1

  GPR61 Inverse agonist 1 (Compound 1) is a GPR61 inverse agonist (IC50: 11 nM).

• GC27810
  Convolamine

  Convolamine is an alkaloid found in Convolvulus pluricaulis and an effective positive modulator of the sigma-1 receptor (IC 50 = 289 nM), exhibiting cognitive and neuroprotective properties.

• GC31636
  Cholesteryl linoleate

  A cholesterol ester

• GB60393
  Perfluorooctanesulfonamide

  -

• GC81902
  SR10098

  SR10098 is a benzimidazole-based Nurr1 activator with an EC 50 of 24 nM against full-length Nurr1.

• GC81906
  N-Phenyl-1H-benzimidazol-6-amine

  -

• GC81904
  5MPEP

  -

• GC81903
  Zaloganan acetate

  -

• GN10700
  Plantamajoside

  Plantamajoside is a phenylpropanoid glycoside compound with NF-κB and MAPK signaling pathway inhibition and antioxidant activity.

• GC11108
  Abiraterone acetate

  A CYP17A1 inhibitor

• GC81901
  M918 acetate

  -

• GC81905
  α-Methyl-L-tryptophan

  -

• GC39005
  Nordalbergin

  Nordalbergin, a coumarin isolated from the wood bark of Dalbergia sissoo. Nordalbergin shows strong activity in the induction of differentiation of HL-60.

• GC37999
  β-Anhydroicaritin

  β-Anhydroicaritin is isolated from Boswellia carterii Birdware, has important biological and pharmacological effects, such as antiosteoporosis, estrogen regulation and antitumor properties.

• GC39731
  Warfarin sodium

  Warfarin sodium is an orally active vitamin K antagonist.

• GC19992
  Clodronate Liposomes

  Macrophage scavenger - Clodronate Liposomes Clodronate Liposomes were developed by Professor Nico van Rooijen of Vrije University in Amsterdam, Netherlands, introduces membrane-impermeable clodronate into the cell through the entosis mechanism of macrophages. Under the action of macrophage lysosomal phosphatase, clodronate dissolved in the aqueous phase of liposomes is released and accumulated in the cells. When it reaches a certain concentration, it can induce macrophages to enter the apoptosis process, and then the macrophages were eliminated. Clodronate Liposomes are suitable for various injection methods, such as intravenous injection, intraperitoneal injection, subcutaneous injection, intranasal injection and testicular injection, etc. The injection volume is related to the body weight of the mice, the injection period, the injection method and the purpose of the experiment. Solution 10 mM Na 2 HPO 4 , 10 mM NaH 2 PO 4 , 140 mM NaCl Concentration 5 mg/mL Lipid composition Phosphatidylcholine and cholesterol Structure

• GC27581
  Control Liposomes(PBS)

  Disodium clodronate is a specific macrophage-killing agent that can eliminate macrophages in tissues by inducing macrophage apoptosis.

• GC49443
  7α-hydroxy Cholesterol

  7α-hydroxy Cholesterol is an endogenous oxidized cholesterol metabolite.

• GC31360
  Taspoglutide (ITM077)

  Taspoglutide (ITM077) is a novel analog of human glucagon-like peptide-1 [hGLP-1(7-36)NH 2 ] in clinical development for the treatment of type 2 diabetes. Taspoglutide inhibits VEGFR2 in CHO cells with an IC 50 value of 4.6±0.6nM.

• GC70621
  NBD-Pen

  NBD-Pen is a high-sensitivity, specific fluorescence probefor lipid radicals (λex: 478 nm, λem: 534 nm).

• GC15161
  Calcium D-Panthotenate

  Calcium D-Panthotenate (Vitamin B5 calcium salt), a vitamin, can reduce the patulin content of the apple juice.

• GC14927
  Trazodone HCl

  Trazodone (hydrochloride) (AF-1161) is an antidepressant belonging to the class of serotonin receptor antagonists and reuptake inhibitors for treatment of anxiety disorders.

• GC26002
  Trazodone

  Trazodone is a 5-hydroxytryptamine antagonist and reuptake inhibitor (SARI).

• GC30112
  PAT-1251

  PAT-1251 is a lysyl oxidase-like 2 (LOXL2; IC 50 =0.71μM) inhibitor.

• GC40781
  11(Z),14(Z),17(Z)-Eicosatrienoic Acid

  11(Z),14(Z),17(Z)-Eicosatrienoic Acid is an ω-3 long-chain polyunsaturated fatty acid and an endogenous metabolite, can serve as a metabolic intermediate in the conversion of α-linolenic acid to long-chain ω-3 fatty acids such as EPA and DHA.

• GC13645
  nor-Binaltorphimine dihydrochloride

  nor-Binaltorphimine dihydrochloride is a potent and selective κ opioid receptor (KOR) antagonist.

• GC63604
  Sparfosic acid

  Sparfosic acid, a DNA antimetabolite agent, is a potent inhibitor of aspartate transcarbamoyl transferase, the enzyme catalyzing the second step of de novo pyrimidine biosynthesis.

• GC33094
  GC7 Sulfate

  GC7 Sulfate is the sulfate salt of N1-guanyl-1,7-diaminoheptane and a deoxyhypusine synthase (DHPS) inhibitor.

• GC30183
  Acridine Orange 10-Nonyl Bromide (Nonylacridine orange)

  Acridine Orange 10-Nonyl Bromide (Nonylacridine orange) is a mitochondria-targeting fluorescent probe (excitation wavelength: 489nm; emission wavelength: 525nm).

• GC62372
  Cyclic-di-GMP sodium

  Cyclic-di-GMP sodium is a STING agonist and a bacterial second messenger that coordinates different aspects of bacterial growth and behavior, including motility, virulence, biofilm formation, and cell cycle progression. Cyclic-di-GMP sodium has anti-cancer cell proliferation activity and also induces elevated CD4 receptor expression and cell cycle arrest. Cyclic-di-GMP sodium can be used in cancer research.

• GC60186
  HBC620

  HBC620 is an HBC-like fluorophore, a GFP fluorophore-like synthetic dye, with a maximum excitation wavelength of 577nm and a maximum emission wavelength of 620nm.

• GC50244
  4-ethynyl-N-ethyl-1,8-naphthalimide

  Click-activated fluorescent probe

• GN10341
  Acetate gossypol

  Acetate gossypol is a lipid-soluble polyphenolic compound extracted from the cotton plant with antifertility, antioxidant, and anticancer properties.

• GN10082
  Gossypol

  Gossypol is a lipid-soluble polyphenolic compound extracted from the cotton plant with antifertility, antioxidant, and anticancer properties.