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Reactive Oxygen Species

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Reactive oxygen species (ROS), such as superoxide anion (O2-), hydrogen peroxide (H2O2), and hydroxyl radical (HO•), consist of radical and non-radical oxygen species formed by the partial reduction of oxygen. Cellular ROS are generated endogenously during mitochondrial oxidative metabolism as well as in cellular response to xenobiotics, cytokines, and bacterial invasion.

ROS also activates MAPK pathways by the direct inhibition of MAPK phosphatases. Through PTEN, the PI3K pathway is subject to reversible redox regulation by ROS generated by growth factor stimulation. The activation of autophagy may be a cellular defense mechanism in response to ROS.

Products Related to Reactive Oxygen Species(505)

  • GC91783 structure
    GC91783FA16
    Purity: >95.00%

    FA16 is a ferroptosis inducer and an inhibitor of the system xc- cystine/glutamate transporter.

  • GC91887 structure
    GC91887Methyl Salicylate-d4
    CAS: 1219802-12-6
    Purity: >99.00%

    تم تصميم Methyl Salicylate-d4 للاستخدام كمعيار داخلي لقياس ساليسيلات الميثيل بواسطة GC أو LC-MS.

  • GC91910 structure
    GC91910Ferroptosis Inhibitor D1
    Purity: >98.00%

    Ferroptosis Inhibitor D1 هو زبال الجذور الحرة و مثبط الفيروبوتسيس.

  • GC92018 structure
    GC92018N,N′-Diferuloylputrescine
    CAS: 42369-86-8
    Purity: >95.00%

    N,N′-Diferuloylputrescine هو متعدد الأمين الذي تم العثور عليه في Z. ميس وله أنشطة بيولوجية متنوعة.

  • GC92043 structure
    GC920439(10)-Nitrooleate
    CAS: 1092676-99-7
    Purity: >95.00%

    9(10)-Nitrooleate هو مزيج من جزيئات إشارات الدهون الذاتية نيتروألكين 9-nitrooleate.

  • GC92088 structure
    GC92088GLP-1 (28-36) amide (trifluoroacetate salt)
    Purity: >98.00%

    الببتيد الشبيه بالجلوكاغون 1 GLP-1 (28-36) amide (trifluoroacetate salt) هو ببتيد ومستقلب نشط من ناهض GLP-1R ذاتي المنشأ GLP-1 (7-36) أميد.

  • GN10006 structure
    GN100063,4-Dihydroxybenzaldehyde
    CAS: 139-85-5
    Purity: >99.50%
  • GN10041 structure
    GN10041Isoquercitrin
    CAS: 21637-25-2
    Purity: >98.50%
  • GN10074 structure
    GN10074Xanthotoxol
    CAS: 2009-24-7
    Purity: >98.00%
  • GN10098 structure
    GN10098Glabridin
    CAS: 59870-68-7
    Purity: >97.00%
  • GN10120 structure
    GN10120Pinocembrin
    CAS: 480-39-7
    Purity: >99.00%

    Pinocembrin is a flavonoid compound and a competitive histidine decarboxylase (HDC) inhibitor.

  • GN10132 structure
    GN10132Schizandrin B
    CAS: 61281-37-6
    Purity: >98.00%

    Schizandrin B is a kind of natural compounds which isolated from Schisandra chinensis , possesses a variety of pharmacokinetic properties, including antioxidant, anti-inflammatory, cardiacprotection and neuroprotection.

  • GN10208 structure
    GN10208Berberine hydrochloride
    CAS: 633-65-8
    Purity: >97.00%

    Berberine hydrochloride is a bioactive alkaloid of the isoquinoline class derived from the medicinal plant Coptis chinensis of the Ranunculaceae family, possessing a wide range of pharmacological functions with applications in cancer, inflammation, diabetes, depression, hypertension, and various infections.

  • GN10221 structure
    GN10221Berberine
    CAS: 2086-83-1
    Purity: >99.50%

    البربيرين (الأصفر الطبيعي 18) هو قلويد معزول من الطب الصيني التقليدي Huanglian، كمضاد حيوي. يحفز البربيرين (الأصفر الطبيعى 18) إنتاج جذور أكسجة نشطة و يثبط توبوإزميراز دنا.

  • GN10237 structure
    GN10237Protopine
    CAS: 130-86-9
    Purity: >99.50%

    Protopine, an alkaloid derived from Corydalis ternata , inhibits acetylcholinesterase activity with an IC 50 value of 50μM.

  • GN10264 structure
    GN10264Isochlorogenic acid A
    CAS: 2450-53-5
    Purity: >98.00%
  • GN10276 structure
    GN10276Naringenin
    CAS: 480-41-1
    Purity: >98.50%

    Naringenin is a citrus flavonoid compound that can be used to treat cancer and has antioxidant and anti-inflammatory activities.

  • GN10292 structure
    GN10292Silibinin
    CAS: 22888-70-6
    Purity: >98%

    Silibinin is an orally active flavonoid with hepatoprotective and anticancer effects.

  • GN10298 structure
    GN10298Albiflorin
    CAS: 39011-90-0
    Purity: >98.00%

    Albiflorin, a principal monoterpene glycoside, exhibits strong pharmacological effects in combating inflammation, oxidation and apoptosis.

  • GN10308 structure
    GN10308Chlorogenic acid
    CAS: 327-97-9
    Purity: >98.00%

    حمض الكلوروجينيك هو مركب فينولي رئيسي في القهوة والشاي.

  • GN10325 structure
    GN10325Nobiletin
    CAS: 478-01-3
    Purity: >99.00%

    Nobiletin is a polymethoxylated flavone extracted from citrus plants. Nobiletin has a variety of pharmacological effects, including antioxidant, anti-inflammatory, and anti-tumor properties.

  • GN10356 structure
    GN10356Calycosin-7-glucoside
    CAS: 20633-67-4
    Purity: >99.50%
  • GN10388 structure
    GN10388Gallic acid
    CAS: 149-91-7
    Purity: >99.00%

    Gallic acid is a 3,4,5-trihydroxybenzoic acid phenolic compound with antioxidant, anti-inflammatory and antitumor activities.

  • GN10422 structure
    GN10422Echinacoside
    CAS: 82854-37-3
    Purity: >98.00%

    Echinacoside is a phenylethanoid glycoside isolated from Cistanche tubulosa with potent antioxidant and anti-inflammatory effects.