ERK
ERK (extracellular-signal-regulated kinase), also known as MAPK, is involved in the regulation of meiosis, mitosis, and postmitotic functions in differentiated cells.
Products Related to ERK(134)
- GC81556FZ1 peptidePurity: >99.50%
FZ1 peptide is a cyclic heptapeptide and also an integrin αvβ3 agonist.
- GC81572Glutathione trisulfide TFAPurity: >99.00%
Glutathione trisulfide TFA (GSSSG TFA) is an orally active, blood-brain barrier permeable neuroprotective agent.
- GC81682Sialorphin TFAPurity: >97.00%
Sialorphin TFA is a neutral endopeptidase ( NEP ) and aminopeptidase N ( APN ) inhibitor that responds to androgen signals.
- GC81731Hericene ACAS: 157207-54-0Purity: >98.50%
Hericene A is an orally active aromatic hericene derivative.
- GC81771RANKL-IN-1 formatePurity: >99.50%
RANKL-IN-1 formate is a selective receptor activator of nuclear factor-κB ligand inhibitor ligand ( RANKL ) inhibitor with a K D value of 7.6 μM.
- GF10303Lipoteichoic acidCAS: 56411-57-5
Lipoteichoic acid is a teichoic acid predominantly located in the cell walls of Gram-positive bacteria, widely involved in stimulating immune responses and cellular signaling pathways.
- GN10494Astragaloside IVCAS: 84687-43-4Purity: >98.00%
Astragaloside IV, an active component isolated from Astragalus membranaceus, can protect the myocardium against ischemia/reperfusion injury and Inhibits HAdV-3 replication and reduces HAdV-3-induced apoptosis.
- GN10664HonokiolCAS: 35354-74-6Purity: >98.50%
Honokiol is a natural bisphenol chemical with multiple biological activities. It targets multiple signaling molecules and has effective antioxidant, anti-inflammatory, anti-angiogenic and anti-cancer activities. It also has broad-spectrum antibacterial and anti-human immunodeficiency virus (HIV) activities.
- GC17031VRT752271CAS: 869886-67-9Purity: >99.50%
VRT752271 (BVD-523 ؛ VRT752271) هو مثبط تساهمي فعال عن طريق الفم وانتقائي للغاية وقابل للانعكاس من ATP من كينازات ERK1 / 2 ، مع IC50 <0.3 نانومتر ضد ERK2. VRT752271 (BVD-523 ؛ VRT752271) يمنع ERK2 الفسفوري (pERK) و kinase RSK المصب (pRSK) في خط خلايا سرطان الجلد A375.
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GC81556 | FZ1 peptide | - | >99.50% | |
FZ1 peptide is a cyclic heptapeptide and also an integrin αvβ3 agonist. | ||||
| GC81572 | Glutathione trisulfide TFA | - | >99.00% | |
Glutathione trisulfide TFA (GSSSG TFA) is an orally active, blood-brain barrier permeable neuroprotective agent. | ||||
| GC81673 | UE01 | 486440-74-8 | >98% | |
UE01 is an orally active, selective small-molecule modulator targeting both ULK1/ERK1/2. | ||||
| GC81682 | Sialorphin TFA | - | >97.00% | |
Sialorphin TFA is a neutral endopeptidase ( NEP ) and aminopeptidase N ( APN ) inhibitor that responds to androgen signals. | ||||
| GC81731 | Hericene A | 157207-54-0 | >98.50% | |
Hericene A is an orally active aromatic hericene derivative. | ||||
| GC81771 | RANKL-IN-1 formate | - | >99.50% | |
RANKL-IN-1 formate is a selective receptor activator of nuclear factor-κB ligand inhibitor ligand ( RANKL ) inhibitor with a K D value of 7.6 μM. | ||||
| GF10303 | Lipoteichoic acid | 56411-57-5 | - | |
Lipoteichoic acid is a teichoic acid predominantly located in the cell walls of Gram-positive bacteria, widely involved in stimulating immune responses and cellular signaling pathways. | ||||
| GN10267 | Loureirin B | 119425-90-0 | >99.00% | |
| GN10481 | Corynoxeine | 630-94-4 | >99.50% | |
| GN10494 | Astragaloside IV | 84687-43-4 | >98.00% | |
Astragaloside IV, an active component isolated from Astragalus membranaceus, can protect the myocardium against ischemia/reperfusion injury and Inhibits HAdV-3 replication and reduces HAdV-3-induced apoptosis. | ||||
| GN10664 | Honokiol | 35354-74-6 | >98.50% | |
Honokiol is a natural bisphenol chemical with multiple biological activities. It targets multiple signaling molecules and has effective antioxidant, anti-inflammatory, anti-angiogenic and anti-cancer activities. It also has broad-spectrum antibacterial and anti-human immunodeficiency virus (HIV) activities. | ||||
| GN10752 | Pachymic acid | 29070-92-6 | >98.00% | |
| GC17031 | VRT752271 | 869886-67-9 | >99.50% | |
VRT752271 (BVD-523 ؛ VRT752271) هو مثبط تساهمي فعال عن طريق الفم وانتقائي للغاية وقابل للانعكاس من ATP من كينازات ERK1 / 2 ، مع IC50 <0.3 نانومتر ضد ERK2. VRT752271 (BVD-523 ؛ VRT752271) يمنع ERK2 الفسفوري (pERK) و kinase RSK المصب (pRSK) في خط خلايا سرطان الجلد A375. | ||||
| GC10647 | FR 180204 | 865362-74-9 | >98.00% | |
FR 180204 هو مثبط ERK انتقائي وتنافسي ATPيثبط FR 180204 ERK1 و ERK2 مع IC50s من 0.51 ميكرومتر (Ki = 0.31 ميكرومتر) و 0.33 ميكرومتر (Ki = 0.14 ميكرومتر) ، على التوالي | ||||