GLPBio

Aromatase

Aromatase is an enzyme which belongs to the cytochrome p450 superfamily. It localizes on the endoplasmic reticulum of estrogen producing cell and catalyzes the final step of estrogen biosynthesis, converting androgen to estrogens.

Products Related to Aromatase(12)

  • GC10256 structure
    GC10256Anastrozole
    CAS: 120511-73-1
    Purity: >99.50%

    Aromatase inhibitor

  • GC10726 structure
    GC10726Letrozole
    CAS: 112809-51-5
    Purity: >98.00%

    Letrozole (CGS 20267) is an orally active nonsteroidal selective aromatase inhibitor with an IC 50 of 11.5nM.

  • GC11813 structure
    GC11813Exemestane
    CAS: 107868-30-4
    Purity: >99.50%

    Steroidal aromatase inhibitor,selective and irreversible

  • GC16433 structure
    GC16433Aminoglutethimide
    CAS: 125-84-8
    Purity: >98.50%

    Aromatase inhibitor

  • GC12140 structure
    GC12140Endoxifen
    CAS: 112093-28-4
    Purity: >98%

    Endoxifen Z-isomer is the most important Tamoxifen metabolite responsible for eliciting the anti-estrogenic effects of this drug in breast cancer cells expressing estrogen receptor-alpha (ERα).

  • GC12890 structure
    GC12890α-Naphthoflavone
    CAS: 604-59-1
    Purity: >99.00%

    α-Naphthoflavone is a flavonoid, acts as a potent and competitive aromatase inhibitor with an IC50 and a Ki of 0.5 and 0.2 μM, respectively.

  • GC18301 structure
    GC18301Fadrozole (hydrochloride)
    CAS: 102676-31-3
    Purity: >99.00%

    Fadrozole is a non-steroidal aromatase inhibitor (IC50s = 5 and 1.4 nM for human placental and rat ovarian microsomal aromatase, respectively).

  • GC19151 structure
    GC19151Fadrozole
    CAS: 102676-47-1
    Purity: >99.50%

    Fadrozole (CGS 16949A) is a selective, non-steroidal aromatase inhibitor with an IC 50 value of 4.5μM.

  • GC38682 structure
    GC38682Flavanone
    CAS: 487-26-3
    Purity: >98.00%

    Flavanone is a naturally occurring flavone. Flavanone has inhibitory activity for human estrogen synthetase (aromatase).

  • GC63755 structure
  • GN10457 structure
    GN10457Oleuropein
    CAS: 32619-42-4
    Purity: >98.00%

    Oleuropein is the major phenolic compound in the olive tree, with potent antioxidant and anti-inflammatory properties.

  • GC12815 structure
    GC12815Formestane
    CAS: 566-48-3
    Purity: >98.00%

    Type I steroidal aromatase inhibitor