CHIR98024 is an inhibitor of glycogen synthase kinase 3 (GSK3; IC50 = 0.56 nM).1
1.Wagman, A.S., Johnson, K.W., and Bussiere, D.E.Discovery and development of GSK3 inhibitors for the treatment of type 2 diabetesCurr. Pharm. Des.10(10)1105-1137(2004)
CHIR98024
Catalog No.: GC49392Purity:>95.00%Synonyms: CT 98024
A GSK3 inhibitor
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 556813-39-9
1 mgIn Stock
$68.00
1
5 mgIn Stock
$216.00
1
10 mgIn Stock
$396.00
1
25 mgIn Stock
$902.00
1
| Pack Size | Price | Availability | Quantity | Action |
|---|---|---|---|---|
| 1 mg | $68.00 | In Stock | 1 | |
| 5 mg | $216.00 | In Stock | 1 | |
| 10 mg | $396.00 | In Stock | 1 | |
| 25 mg | $902.00 | In Stock | 1 |
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Citations
No citations are currently available for this product. Below are selected publications citing GlpBio products.
Nature641, 529–536 (2025)
Nature628, 630–638 (2024)
Nature632, 686–694 (2024)
Nature618, 1017–1023 (2023)
Nature610, 366–372 (2022)
Cell187(9):2288-2304 (2024)
Cell183(7):1867-1883 (2020)
Science388(6745) (2025)
Science387(6739) (2025)
Science387(6734) (2025)
Cell Research35, 97–116 (2025)
Cell Research34, 683–706 (2024)
Cell Research33, 273–287 (2023)
Cell Research33, 546–561 (2023)
Cell Research33, 904–922 (2023)
Cell Research31, 1291–1307 (2021)
Description
Product Documents
Purity:>95.00%Appearance:A solid
Chemical Properties
CAS No.
556813-39-9
Synonyms
CT 98024
SMILES
NC1=NC(NCCNC2=NC=C(C3=NC=CN3)C(C4=C(Cl)C=C(Cl)C=C4)=N2)=CC=C1[N+]([O-])=O
Molecular Formula
C20H17Cl2N9O2
Molecular Weight
486.3
Solubility
DMSO: slightly soluble,Ethanol: slightly soluble
Storage
-20°C
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.
CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility
g/mol
Reviews
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