GLPBio

CPD-39

Catalog No.: GC82653Purity:>98.00%
CPD-39 is a potent and orally active CCND1 and CDK4 heterobifunctional PROTAC degrader.

Products are for research use only. Not for human use. We do not sell to patients.


CPD-39
Cas No.: 3055472-38-0
10mM (in 1mL DMSO)In Stock
$1,103.00
1
1mgIn Stock
$225.00
1

Citations

No citations are currently available for this product. Below are selected publications citing GlpBio products.
  • Nature cover
    Nature
    641, 529–536 (2025)
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    Nature
    628, 630–638 (2024)
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    Nature
    632, 686–694 (2024)
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    618, 1017–1023 (2023)
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    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
  • Science cover
    Science
    388(6745) (2025)
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    Science
    387(6739) (2025)
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    Science
    387(6734) (2025)
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    Cell Research
    35, 97–116 (2025)
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    Cell Research
    34, 683–706 (2024)
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    33, 273–287 (2023)
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    33, 546–561 (2023)
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    33, 904–922 (2023)
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    Cell Research
    31, 1291–1307 (2021)

Description

CPD-39 is a potent and orally active CCND1 and CDK4 heterobifunctional PROTAC degrader. CPD-39 shows anti-proliferation [1]. (Pink: CDK4 and CCND1 ligand; Blue: VHL ligand; Black: linker ).

References:
[1]. Jing Liu, et al. Compounds and methods of treating cancers. French, WO2024183798A1.

Product Documents

Purity:>98.00%Appearance:A solid

Chemical Properties

CAS No.
3055472-38-0
Molecular Formula
C46H57N15O4
Molecular Weight
884.04
Solubility
DMSO: 100 mg/mL (113.12 mM; Need ultrasonic)
Storage
Store at -20°C
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

Reviews

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