Startseite>>Signaling Pathways>> Membrane Transporter/Ion Channel>> CRAC Channel>>5J 4

5J 4

Katalog-Nr.GC50179

5J 4 ist ein potenter CRAC-Inhibitor.

Products are for research use only. Not for human use. We do not sell to patients.

5J 4 Chemische Struktur

Cas No.: 827001-82-1

Größe Preis Lagerbestand Menge
10 mg
167,00 $
Auf Lager
50 mg
702,00 $
Auf Lager

Tel:(909) 407-4943 Email: sales@glpbio.com

Kundenbewertungen

Basiert auf Kundenrezensionen.

  • GlpBio Citations

    GlpBio Citations
  • Bioactive Compounds Premium Provider

    Bioactive Compounds Premium Provider

Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

Calcium release-activated calcium (CRAC) channel blocker. Blocks store-operated calcium entry (SOCE) in HeLa-O+S cells and Th17 cells in vitro. Ameliorates symptoms and reduces CNS infiltration by mononuclear cells in a mouse model of experimental autoimmune encephalomyelitis (EAE) in vivo.

Kim et al (2014) Calcium signaling via Orai1 is essential for induction of the nuclear orphan receptor pathway to drive Th17 differentiation. J.Immunol. 192 110 PMID:24307733

Bewertungen

Review for 5J 4

Average Rating: 5 ★★★★★ (Based on Reviews and 8 reference(s) in Google Scholar.)

5 Star
100%
4 Star
0%
3 Star
0%
2 Star
0%
1 Star
0%
Review for 5J 4

GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.

Required fields are marked with *

You may receive emails regarding this submission. Any emails will include the ability to opt-out of future communications.