2-Linoleoyl Glycerol (Synonyms: 2LG) |
| Katalog-Nr.GC40400 |
2-Arachidonoyl glycerol (2-AG) has been isolated from porcine brain, and has been characterized as the natural endocannabinoid ligand for the CB1 receptor.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 3443-82-1
Sample solution is provided at 25 µL, 10mM.
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2-Arachidonoyl glycerol (2-AG) has been isolated from porcine brain, and has been characterized as the natural endocannabinoid ligand for the CB1 receptor. The congener of 2-AG in which a linoleoyl group replaces the arachidonoyl group is 2-linoleoyl glycerol (2-LG), and this compound also appears in vivo in conjunction with 2-AG. Although the intrinsic activity of 2-LG is low, it potentiates the activity of other endocannabinoids, including 2-AG. This "entourage" effect has been attributed to blockade of the breakdown and reuptake pathways that normally function to reduce endocannabinoid levels rapidly upon release.
Average Rating: 5 (Based on Reviews and 34 reference(s) in Google Scholar.)
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