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AzKTB

Katalog-Nr.GC34337 Copy One-Click Copy Product Info

AzKTB ist ein Fangreagenz, das zwischen dem Azidmodul und den TAMRA/PEG-Biotin-Markierungen eine kurze trypsinspaltbare Peptidsequenz trÄgt.

Products are for research use only. Not for human use. We do not sell to patients.

AzKTB Chemische Struktur

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Sample solution is provided at 25 µL, 10mM.



Description of AzKTB

AzKTB is a capture reagent which bears a short trypsin-cleavable peptide sequence between the azide module and the TAMRA/PEG-biotin labels.

[1]. Wright MH, et al. Validation of N-myristoyltransferase as an antimalarial drug target using an integrated chemical biology approach. Nat Chem. 2014 Feb;6(2):112-21.

Chemical Properties of AzKTB

Cas No. SDF
Canonical SMILES O=C(N[C@@H](CCCCNC(C1=CC=C(C2C3=CC=C(N(C)C)C=C3OC4=C2C=CC(N(C)C)=C4)C(C(O)=O)=C1)=O)C(NCCCOCCOCCOCCCNC(CCCC[C@@H]5SC[C@H]6[C@@H]5NC(N6)=O)=O)=O)CCCCCNC(CNC([C@H](CCCCN)NC([C@@H](NC(CCN=[N+]=[N-])=O)C)=O)=O)=O
Formula C71H106N16O15S M.Wt 1455.76
Löslichkeit Soluble in DMSO Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of AzKTB

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 686.9 μL 3.4346 mL 6.8693 mL
5 mM 137.4 μL 686.9 μL 1.3739 mL
10 mM 68.7 μL 343.5 μL 686.9 μL
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Berechnen

In vivo Formulation Calculator (Clear solution) of AzKTB

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

mg/kg g μL

Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)

% DMSO % % Tween 80 % saline
%DMSO %

Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

Quality Control & SDS

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Average Rating: 5 ★★★★★ (Based on Reviews and 9 reference(s) in Google Scholar.)

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