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EGNHS

Katalog-Nr.GC61794

EGNHS ist ein Alkyl/Ether-basierter PROTAC-Linker, der bei der Synthese von PROTACs verwendet werden kann.

Products are for research use only. Not for human use. We do not sell to patients.

EGNHS Chemische Struktur

Cas No.: 70539-42-3

Größe Preis Lagerbestand Menge
50mg
25,00 $
Auf Lager
100 mg
39,00 $
Auf Lager
250mg
61,00 $
Auf Lager

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Sample solution is provided at 25 µL, 10mM.

Product has been cited by 2 publications

Description Chemical Properties Product Documents Related Products

EGNHS is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

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