LSD1-IN-6 |
| Katalog-Nr.GC36485 |
LSD1-IN-6 (Verbindung 4m) ist ein potenter und reversibler Inhibitor der Lysin-spezifischen Demethylase 1 (LSD1) mit einem IC50 von 123 nM. LSD1-IN-6 erhÖht dimethyliertes Lys4 von Histon H3, zeigt keine Wirkung auf die Expression von LSD1.
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Cas No.: 2035912-43-5
Sample solution is provided at 25 µL, 10mM.
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LSD1-IN-6 (Compound 4m) is a potent and reversible inhibitor of lysine-specific demethylase 1 (LSD1), with an IC50 of 123 nM. LSD1-IN-6 increases dimethylated Lys4 of histone H3, shows no effect on expression of LSD1[1]. IC50: 123 nM (LSD1)[1]
[1]. Duan YC, et al. Discovery of resveratrol derivatives as novel LSD1 inhibitors: Design, synthesis and their biological evaluation. Eur J Med Chem. 2017 Jan 27;126:246-258.
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