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MPT0B390

Katalog-Nr.GC64729

MPT0B390 ist ein Arylsulfonamid-basiertes Derivat mit starker HDAC-InhibitorfÄhigkeit. MPT0B390, TIMP3-Induktor, hemmt Tumorwachstum, Metastasierung und Angiogenese. MPT0B390 zeigt antiproliferative AktivitÄt gegen die menschliche Dickdarmkrebszelllinie HCT116 mit einem GI50 von 0,03 μM.

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MPT0B390 Chemische Struktur

Cas No.: 1817802-18-8

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5 mg
270,00 $
Auf Lager
10 mg
405,00 $
Auf Lager
25 mg
855,00 $
Auf Lager

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents

MPT0B390 is an arylsulfonamide-based derivative with potent HDAC inhibitory ability. MPT0B390, TIMP3 inducer, inhibits tumor growth, metastasis and angiogenesis. MPT0B390 shows antiproliferative activity against human colon cancer cell line HCT116 with the GI50 of 0.03 μM[1].

[1]. Han-Li Huang, et al. TIMP3 expression associates with prognosis in colorectal cancer and its novel arylsulfonamide inducer, MPT0B390, inhibits tumor growth, metastasis and angiogenesis. Theranostics. 2019 Sep 18;9(22):6676-6689.

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