Phen-DC3 |
Katalog-Nr.GC30695 |
Phen-DC3 ist ein G-Quadruplex (G4)-spezifischer Ligand, der FANCJ- und DinG-Helikasen mit IC50-Werten von 65±6 bzw. 50±10 nM hemmen kann.
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Cas No.: 942936-75-6
Sample solution is provided at 25 µL, 10mM.
Phen-DC3 is a G-quadruplex (G4) specific ligand which can inhibit FANCJ and DinG helicases with IC50s of 65±6 and 50±10 nM, respectively.
[1]. Bharti SK, et al. Specialization among iron-sulfur cluster helicases to resolve G-quadruplex DNA structures that threaten genomic stability. J Biol Chem. 2013 Sep 27; 288(39):28217-29.
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